In mismatch repair, how does the cell "know" which strand is the correct strand and which strand is the damaged strand?

Q: What type of repair system would cells most likely use to repair DNA with a deaminated adenine?

A: The spontaneous alteration of the DNA base pairs is needed to undergo the process of DNA repair.…

Q: What is a mutation in DNA repair and recombination?

A: Introduction: DNA damage can happen in various different ways. Some of the damage if left…

Q: What is nucleotide excision repair? What kind of DNA damage does it target for repair?

A: Answer: DNA is deoxynucleotide acid which is the genetic material in many of the organisms as genes…

Q: What are the two major mechanisms for the repair of double-strand breaks? How do they differ?

A: Deoxyribonucleic acid (DNA) is a double stranded helix, which serves as the hereditary unit for…

Q: What is the purpose of DNA methylation? Why is it ineffective in the DNA repair of spontaneous…

A: DNA methylation is the process of adding methyl groups to DNA at Nucleotide bases, so that without…

Q: What is semiconservative replication and how does it work?

A: The process of replication is the formation of a complementary DNA strand from the DNA of the…

Q: What are DNA excision-repair systems?

A: Molecular biology is the field of biology that studies the composition, structure, and interactions…

Q: How is mismatch repair different from excision repair (in terms of what type of mutation it is used…

A: In order to prevent and fix damage from mutation, all the cells have a variety of mechanisms to…

Q: What is the end replication problem?

A: The genes are formed by the Deoxyribonucleic acid (DNA) of an organism. These genes code all of the…

Q: What is meant by a primer, and why are primers necessary for DNA replication?

A: Primers are short DNA or RNA sequences complementary to the existing DNA strands. Without a primer a…

Q: What are the essential differences between base excision repair and nucleotide excision repair and…

A: Nucleic acids are made up of nucleotides, which are the basic building blocks. Long chains of…

Q: What are the three main steps for repairing the DNA damages such as the deamination of cytosine…

A: Despite the elaborate proof-reading employed during DNA synthesis, erros can occur. In addition, DNA…

Q: Among the different types of DNA repair, one has the unique ability to detect which strand is the…

A: A DNA sequence can be changed in the process of DNA replication because of the mistake of DNA…

Q: How does the process of DNA replication generate mismatch mutations? What mechanisms are available…

A: DNA replication is the process in which dsDNA is copied to produce two identical DNA molecules.

Q: What is the difference between leading strand and lagging strand synthesis?

A: DNA is a genetic material which appear as two stranded ladder like structure . It basically…

Q: Why would a cell use SOS repair, considering that it introduces mutations?

A: Answer :- Sos reaction is extreme arrangement when the DNA harm is high that on the off chance that…

Q: What is a template strand or antisense strand?

A: Transcription is the way toward transforming a portion of DNA into RNA. The fragments of DNA…

Q: What would happen if, in the course of replication, the topoisomerases were unable to reattach the…

A: Replication is the process of copying the DNA molecule to form two daughter DNA strands before the…

Q: When the mismatch repair system detects a distortion in the DNA double helix due to a mismatch, what…

A: In the process of DNA (deoxyribonucleic acid) replication, DNA of the cell replicates itself while…

Q: What do you mean by Repair of a Collapsed Replication Fork ?

A: The replication fork is a structure that forms within the long helical DNA during DNA replication.…

Q: What role does DNA methylation play in mismatch repair?

A: DNA methylation is a biochemical process, in which a methyl group is added to the nucleotides of…

Q: During cellular checkpoints DNA Repair Proteins can edit and patch our DNA through many different…

A: Cell cycle is broadly categorized into 2 phases such as interphase and M phase. Interphase consists…

Q: During mismatch repair, why is it necessary to distinguish betweenthe template strand and the newly…

A: Mismatch repair (MMR) is a significant system of repairing deoxyribonucleic acid (DNA) errors in all…

Q: Why is strand separation sometimes beneficial?

A: The biochemical substances that are carried to the succeeding generations are the inheritable…

Q: How does e.coli and human cells distinguish between the old and new strands for mismatch repair?

A: DNA (deoxyribonucleic acid) is the genetic material in all living systems. DNA replication is a…

Q: Which bacterial enzyme is responsible for removing the RNA primer of an Okazaki fragment and…

A: Replication is the process which is responsible for synthesis of DNA from the parent strand.

Q: What types of subunits make up a single strand of DNA? How are the subunits linked?

A: Introduction  DNA strand is composed of three components: Deoxyribose Sugar Nitrogenous Bases…

Q: What is the difference between the template strand and the nontemplate strand?

A: Deoxyribonucleic acid (DNA) is the hereditary unit of life, which carries the genetic information in…

Q: What is the end-replication problem? Why, in the absence of telomerase, do the ends of linear…

A: DNA replication in eukaryotes is semiconservative, semicontinuous, and bidirectional. It occurs in…

Q: Which repair pathway recognizes DNA damage duringtranscription? What happens if the damage is…

A: A gene is the essential physical and functional unit of heredity. They are comprised of DNA…

Q: What is the difference in the requirement for a primer in RNA transcription compared to DNA…

A: DNA replication is the biological process of producing two identical replicas of DNA from one…

Q: In eukaryotic cells, the length of the transcribed RNA is almost equal to the corresponding DNA…

A: Eukaryotic cells are huge and sophisticated creatures having a nucleus encased within the nuclear…

Q: What is an example of a disease or a disorder that results from an error in DNA replication? What…

A: Errors in DNA replication is called as mutation. This results in the change in sequence of DNA which…

Q: hat happens to the ends of linear chromosomes in eukaryotes during replication?

A: DNA replication in eukaryotes is a highly regulated process and usually requires extracellular…

Q: What is the function of the sliding clamp at a replication fork?

A: Replication is a process to produce  daughter DNA from parent DNA. Sliding clamp is a ring shaped…

Q: . Which of the following statements best describe the mismatch repair pathway?a. It is part of the…

A: DNA polymerases include a group of enzymes that are responsible for the synthesis of DNA during DNA…

Q: What is replication slippage?

A: In molecular biology, DNA replication can be described as the process during which DNA is duplicated…

Q: can cells tolerate errors made in transcription in comparison to errors made during DNA replication?

A: RNA polymerase lacks proofreading activity, so the probability of error is more than that of DNA…

Q: How do we know that DNA repair mechanisms detect and correct the majority of spontaneous and induced…

A: DNA can be defined as the deoxyribonucleic acid, which is the molecule that contains the genetic…

Q: Which DNA repair mechanisms makes use of recombination between a damaged strand of a DNA molecule…

A: DNA repair is the set of mechanisms that a cell makes use of to correct damaged DNA so that it can…

Q: How do we know that DNA synthesis is discontinuous on one of the two template strands?

A: DNA replication refers to the process of making two identical copies of a DNA molecule. This…

Q: What is one enzyme that is involved with DNA replication and how would the absence of this enzyme…

A: Introduction: Nucleic acids are major macromolecule present in the nucleus of the cell. DNA is a…

Q: How are deoxyribonucleoside triphosphates (precursors of daughter DNA strands) and ribonucleoside…

A:

Q: In terms of the new DNA strands that are generated, what are the differences between replication and…

A: DNA replication is a biological process which produces two identical DNA from the one original…

Q: What is the difference in DNA replicatoin on the leading strand versus the lagging strand?

A: DNA replication is a semi-discontinuous process as one strand is synthesized continuously whereas…

Q: How does synthesis of the lagging strand differ from that of the leading strand?

A: The cornerstone of life for living things is the transmission of genetic features to the next…

Q: DNA methylation in mismatch repair

A: REPAIR PATHWAYS:- Both in Prokaryotes and Eukaryotes, there is a repair enzyme system to deal with…

Q: Considering prokaryotes, what is the enzyme that synthesizes RNA primers needed to start…

A: DNA replication means the synthesis of daughter DNA strands using the parental strands as a…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.