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- The alternative fate of pyruvate in the mitochondrial matrix is the conversion of pyruvate to __________ catalyzed by __________________ ? Oxaloacetate, pyruvate carboxylase Alanine, alanine aminotransferase Lactate, Lactate dehydrogenase Acetyl-Co, PDHCThe molecule FAD is reduced when an ___________ is oxidized to an ____________. In the citric acid cycle we see this as ______________ gets oxidized to ________________.The oxidation of coenzyme ___________________ provides 1.5 ATP through electron transport.
- Two mobile electron transfer carriers are present in the inner mitochondrial membrane. Name these two carriers.In the 1930s, some physicians prescribed low doses of a compound called dinitrophenol (DNP) to help patients lose weight. This unsafe method was abandoned after some patients died. DNP uncouples the chemiosmotic machinery by making the lipid bilayer of the inner mitochondrial membrane leaky to H+ . Explain how this could cause weight loss and death.In eukaryotic cells, the TCA/citric acid/Kreb's cycle happens in the _______ , while the electron transport chain is in the ________ . cytoplasm; lumen of the lysosome mitochondrial matrix; inner mitochondrial membrane inner mitochondrial membrane; cytoplasm nucleus; mitochondrial matrix
- The role of a subunit of F0 (2 choices are correct) Undergoes multiple conformational changes from lose to tight to open, to synthesize ATP. Uses two half-channels to pick up and release protons. Allows for unidirectional pick up of protons by c subunit. Allows for the import of inorganic phosphate into mitochondrial matrix.Which statement about the ETC is/are FALSE? A. Cytochrome c is freely moving and faces the mitochondrial matrix B. The four respiratory complexes move within the mitochondrial membrane C. CoQ & cytochrome c are not part of the complex but are e- carriers D. CoQ is freely moving within the hydrophilic part of the lipid component of the membraneThis UCP1 protein allows the protons (H+) of the mitochondrial intermembrane space to enter the mitochondrial matrix without going through the ATP synthase. This bypass represents a shortcut for protons and uncouples (i.e. eliminates the interrelationship between) the following two processes: The entry of protons inside the mitochondrial matrix, following their concentration gradient. The phosphorylation of ADP into ATP by the ATP synthase. It is this uncoupling that gave the protein its name: uncoupling protein 1 (UCP1). The following figure shows the location of UCP1 when it is expressed (synthesized) in the brown adipose tissues (BAT) of hibernating mammals. Question 12 Based on the UCP1 protein structure shown earlier, and based on the figure above, what type of protein is UCP1? Question 12 options: a) A primary active transporter. b) A motor protein.…
- Which of the following components of the mitochondrial electron transport chain is the only one to be considered a peripheral protein? cell biology the cytochrome a-a3 complex the cytochrome c oxidase complex coenzyme Q (ubiquinone) the cytochrome b-c1 complex cytochrome cWhich of the following takes place in the mitochondria (including the matrix inner and outer mitochondrial membrane) select all that applies Krebs cycle fatty acid synthesis beta oxidation electron transport chain pdh mechanism glycolysisTrue statements regarding the TCA cycle EXCEPT Its metabolic product is ATP. It produces carbon dioxide and the reducing equivalents NADH and FADH2. It is a process in the mitochondrial matrix. It utilizes a 2-carbon acetyl group, condense with a 4-carbon oxaloacetate to form a tricarboxylic citrate.
