In Sickle Cell Disease, the 6th amino acid after the START codon is different than it is in wildtype hemoglobin. An alignment of HbA DNA (wt) against HbS (sickle allele) is shown below. Arcel is asked to characterize the DNA mutation according to its nucleotide and position. a b C HbA: HbS: Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. d ATG ATG GTG CAC GTG CAC The disease is caused by A20 - T20. The disease is caused by T20-A20. The disease is caused by GAG20-GTG20. CTG GAG ACT CCT GTG CTG ACT CCT The disease is caused by GTG21-GAG21. *** ... Op

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question
In Sickle Cell Disease, the 6th amino acid after the START codon is different than it is in wildtype hemoglobin. An alignment of HbA
DNA (wt) against HbS (sickle allele) is shown below. Arcel is asked to characterize the DNA mutation according to its nucleotide
and position.
r
+
2
HbA: ATG
HbS:
GTG CAC CTG ACT CCT GAG
CAC
CAC CTG ACT
ACT
CCT
GTG
Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer.
ATG GTG
The disease is caused by A20 - T20.
The disease is caused by T20 - A20.
The disease is caused by GAG20 - GTG20.
The disease is caused by GTG21 - GAG21
☐
Transcribed Image Text:In Sickle Cell Disease, the 6th amino acid after the START codon is different than it is in wildtype hemoglobin. An alignment of HbA DNA (wt) against HbS (sickle allele) is shown below. Arcel is asked to characterize the DNA mutation according to its nucleotide and position. r + 2 HbA: ATG HbS: GTG CAC CTG ACT CCT GAG CAC CAC CTG ACT ACT CCT GTG Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. ATG GTG The disease is caused by A20 - T20. The disease is caused by T20 - A20. The disease is caused by GAG20 - GTG20. The disease is caused by GTG21 - GAG21 ☐
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 4 steps

Blurred answer
Knowledge Booster
Genome annotation
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education