In TCA cycle, FADH2 is formed in reaction(s) catalyzed by a. Succinyl-CoA synthetase b. Succinate dehydrogenase O c. Aconitase O d. Isocitrate dehydrogenase e. Citrate synthase
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- A. What is substrate level phosphorylation. B. Although oxygen does not participate directly in the citric acid cycle , the cycle only operates when oxygen is present. Why is this so so ? C.describe how hibernating animals and new born babies are able to keep warm without shivering. D. What is the metabolic purpose of hexose monophospate shunt pathway E.hg does G6PD deficient individuals have increase in resistance to malaria?The pathway that converts glucose to acetyl-CoA is often referred to as an “aerobic oxidation pathway.” (a) Is molecular boxygen involved in any of the steps of glycolysis? (b) Thinking back to Chapter 20, where does molecular oxygen enter the picture?Which of the following statements about the ß-oxidation cycle is/are TRUE?A. The fatty acyl produced is shorter by 2 carbon atoms than the previous cycle.B. The two oxidation reactions involve both NADH and NADPH.C. Acetyl-CoA is produced in the hydration reaction.D. In the cleavage reaction, the bond between the α- and β- carbons become a double bund.
- Oxidative decarboxylation a. Do not occur in the TCA cycle. b. Involve loss of CO2 and the production of NADH. c. Involve loss of CO2 and the production of NAD. d. Involve loss of CO2 and the production of FADH2.When one acetyl CoA is processed through the citric acid cycle, how many times does each of the following events occur? a. A FAD molecule is a reactant. b. A CoA-SH molecule is produced. c. A dehydrogenase enzyme is needed for the reaction to occur. d. A C5 molecule is produced.During the process of oxidizing palmitate (C16) for fuel, 3-hydroxypalmitoyl CoA __________. Choose ALL that apply. (A) is oxidized by FAD(B) is oxidized by NAD+(C) is a substrate for b-ketothiolase(D) undergoes a hydration(E) is a product of enoyl CoA hydratase(F) is attacked by a CoA molecule to produce acetyl CoA and a C14 acyl CoA
- There are two steps in the TCA cycle that involve the release of free CoA-SH. However, only one of these steps is regulated (i.e. only one of the steps has a large negative delta G). Explain why one of these CoA-SH releasing steps is highly thermodynamically favorable while the other is not.Which of the following stimulates the conversion of pyruvate to acetyl-CoA? a) Activation of pyruvate dehydrogenase kinase b) A decrease in the ratio of NAD+/NADH c) Bothaandb d) Neither a nor bIf you fed a mouse a diet made up of exclusively Leucine, the mouse would eventually: A、Undergo extensive gluconeogenesis B、Enter ketosis C、Have a buildup of α-Ketoglutarate D、gain weight E、have a buildup of succinyl-CoA
- myristic acid (14:0) to carbon dioxide and watera. rounds of the beta oxidation pathway will be involvedb. how many moles of acetyl CoA will be produced after complete beta oxidationc. how many moles of ATP will be obtained after complete beta oxidationPharmaceuticals in a class called the statins inhibit theenzyme HMG-CoA reductase. What is the primary effect ofthis drug on patients?The metabolic function of the pentose phosphate pathway is to: a. generate NADPH and pentoses for the biosynthesis of fatty acids and nucleic acids. b. provide intermediates for the citric acid cycle c. participate in oxidation-reduction reactions during the formation of H,O d. act as a source of ADP for biosynthesis