In the attached image shows the charge in concentration of caspase 3 and 9 in cells of two different cancer cell lines following exposure to concentrations of the drug bafilomycin A1. -Describe the effect of Bafilomycin A1 on caspase 3 and caspase 9 in the cell lines. -Based on the above, what would you expect to happen to cells exposed to Bafilomycin A1?

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In the attached image shows the charge in concentration of caspase 3 and 9 in cells of two different cancer cell lines following exposure to concentrations of the drug bafilomycin A1. -Describe the effect of Bafilomycin A1 on caspase 3 and caspase 9 in the cell lines. -Based on the above, what would you expect to happen to cells exposed to Bafilomycin A1?
0.4
Bafilomycin A1
O OnM
0.3-
O100nM
200nM
400nM
0.2-
0.1-
BEL-7402
HO-8910
BEL-7402
HO-8910
Caspase-3
Caspase-9
Proportional change in
caspase activation
Transcribed Image Text:0.4 Bafilomycin A1 O OnM 0.3- O100nM 200nM 400nM 0.2- 0.1- BEL-7402 HO-8910 BEL-7402 HO-8910 Caspase-3 Caspase-9 Proportional change in caspase activation
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based on the above graph, what would you expect to happen to cells exposed to bafilomycin A1? Justify your answer. 

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