In the biosynthesis of heme, ring cyclization, isomerization, and decarboxylation reactions take place. Identify the potential intermediates and show the electron flow in the following diagram.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter21: Photosynthesis
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In the biosynthesis of heme, ring cyclization, isomerization, and decarboxylation reactions take place. Identify the
potential intermediates and show the electron flow in the following diagram.
HO,C
R1
HO2C-
-R2
NH HN-
но-
NH HN-
HO2C
R
R2
unstable intermediate
Uro'gen II
HO2C
Me
Me
NH HN-
-CO2H
HN
NH
Me
Me
HO2C
CO2H
Coproporphyrinogen II
Transcribed Image Text:In the biosynthesis of heme, ring cyclization, isomerization, and decarboxylation reactions take place. Identify the potential intermediates and show the electron flow in the following diagram. HO,C R1 HO2C- -R2 NH HN- но- NH HN- HO2C R R2 unstable intermediate Uro'gen II HO2C Me Me NH HN- -CO2H HN NH Me Me HO2C CO2H Coproporphyrinogen II
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