In the preparation of p-Nitroaniline, there are three synthetic steps in this reaction, the first is acetylation of the amine, second is nitrates and the third is hydrolysis of the amide. Why must acetylation be done first if at all? Use chemical structures to illustrate your point.

In the preparation of p-Nitroaniline, there are three synthetic steps in this reaction, the first is acetylation of the amine, second is nitrates and the third is hydrolysis of the amide. Why must acetylation be done first if at all? Use chemical structures to illustrate your point.

Macroscale and Microscale Organic Experiments

7th Edition

ISBN:9781305577190

Author:Kenneth L. Williamson, Katherine M. Masters

Publisher:Kenneth L. Williamson, Katherine M. Masters

Chapter43: Amines

Section: Chapter Questions

Problem 7Q

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