Individuals who possess a C allele at the R$429358 SNP, located in the 4th Exon of the ApoE gene, are more likely to have a variant at the ApoE protein that can increase the risk of Alzheimer's disease over a T allele. You are running a set of samples on a SNP chip and determine that your population has 2 CC individuals, 16 CT individuals, and 32 TT individuals. The C and T alleles in the ApoE gene are segregating at the frequencies observed in the 1st generation you observe the population. If you assume a standard Wright-Fisher model of genetic drift, what is the expected probability of eventual fixation of the T allele? Is this a certain outcome?
Individuals who possess a C allele at the R$429358 SNP, located in the 4th Exon of the ApoE gene, are more likely to have a variant at the ApoE protein that can increase the risk of Alzheimer's disease over a T allele. You are running a set of samples on a SNP chip and determine that your population has 2 CC individuals, 16 CT individuals, and 32 TT individuals. The C and T alleles in the ApoE gene are segregating at the frequencies observed in the 1st generation you observe the population. If you assume a standard Wright-Fisher model of genetic drift, what is the expected probability of eventual fixation of the T allele? Is this a certain outcome?
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter18: Dna Technologies: Making And Using Genetically Altered Organisms, And Other Applications
Section: Chapter Questions
Problem 1ITD: You learned in the chapter that an STR locus is a locus where alleles differ in the number of copies...
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