Answered: The use of nucleotide sequence data to…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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The use of nucleotide sequence data to measure genetic variability
is complicated by the fact that the genes of many eukaryotes
are complex in organization and contain 5' and 3' flanking
regions as well as introns. Researchers have compared the
nucleotide sequence of two cloned alleles of the y-globin gene from a
single individual and found a variation of 1 percent. Those differences
include 13 substitutions of one nucleotide for another
and three short DNA segments that have been inserted in one
allele or deleted in the other. None of the changes takes place
in the gene’s exons (coding regions). Why do you think this is
so, and should it change our concept of genetic variation?

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