Inherited cancers are due to mutations in ________ cells. They are/are not passed on to offspring. Sporadic cancers are due to mutations in __________ cells. They are/are not passed on to offspring. Inherited cancers are more/less common than sporadic cancers. Do you think Kay’s cancer is inherited or sporadic? Why? (1-2 sentences only)

Inherited cancers are due to mutations in cells. They are/are not passed on to offspring. Sporadic cancers are due to mutations in __ cells. They are/are not passed on to offspring. Inherited cancers are more/less common than sporadic cancers. Do you think Kay’s cancer is inherited or sporadic? Why? (1-2 sentences only)

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter12: Genes And Cancer

Section: Chapter Questions

Problem 22QP: In Section 12-1, Julie is concerned that she may develop breast cancer, but testing shows that she...

See similar textbooks

Similar questions

Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. A man who had hemophilia (an X-linked recessive genetic disorder), married a woman who had no family history of hemophilia whatsoever. The couple had consulted a genetic counselor when they first contemplated having children due to concerns that their future children might have hemophilia. Genetic testing of both future parents revealed that the husband did, in fact, possess the Hemophilia A allele but his wife was completely normal with respect to hemophilia. Much to their shock, their first child, a daughter, had a mild blood clotting disorder. Karyotyping was performed to determine whether this daughter had an…
Both have a genetic disorder, but they already have one child who does not have the disorder. They would like to have more children and were told by a friend that since their first child was normal their future children would be normal as well. Explain to them the probability of future offspring being normal or having the disease (assume that this is an autosomal disease). Be sure to tell them whether the disease is brought about by a dominant or recessive allele and what fraction of their children (if any) could be carriers for the disease.
Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. A young couple, Bart and Jenny, are expecting a child and are aware there might be a chance that their child could be affected by this disorder. Jenny (the wife) has ichthyosis, but Bart (her husband) is unaffected and completely normal with respect to the allele responsible for this disorder. Both Bart and Jenny were Biology majors as undergraduates. Knowing a little about the pattern of X-linked recessive inheritance, Bart and Jenny were concerned when ultrasound revealed that they would be having a son. However, genetic testing performed on the baby shortly after birth revealed that their newborn son, Mark, did not…
Why doesn’t the father (II-1) have the disease breast cancer? What is the formal name for an individual having the gene but not showing the trait?
The following family has a history of inherited breast cancer. Betty (grandmother) does not carry the gene. Don, her husband, does. Dons mother and sister had breast cancer. One of Betty and Dons daughters (Sarah) has breast cancer; the other (Karen) does not. Sarahs daughters are in their 30s. Dawn, 33, has breast cancer; Debbie, 31, does not. Debbie is wondering if she will get the disease because she looks like her mother. Dawn is wondering if her 2-year-old daughter (Nicole) will get the disease. a. Draw a pedigree indicating affected individuals and identify all individuals. b. What is the most likely mode of inheritance of this trait? c. What are Dons genotype and phenotype? d. What is the genotype of the unaffected women (Betty and Karen)? e. A genetic marker has been found that maps very close to the gene. Given the following marker data for chromosomes 4 and 17, which chromosome does this gene map to? f. Using the same genetic marker, Debbie and Nicole were tested. The results are shown in the following figure. Based on their genotypes, is either of them at increased risk for breast cancer?
If your father were diagnosed with an inherited disease that develops around the age of 50, would you want to be tested to find out whether you would develop this disease? If so, when would you want to be tested? As a teenager or sometime in your 40s? If not, would you have children?
If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this an indication that there is a genetic contribution to these traits? What would you do to confirm that genetics is involved in this condition?
A couple has had a child born with neurofibromatosis. They come to your genetic counseling office for help. After taking an extensive family history, you determine that there is no history of this disease on either side of the family. The couple wants to have another child and wants to be advised about the risks of that child having neurofibromatosis. What advice do you give them?
In Section 12-1, Julie is concerned that she may develop breast cancer, but testing shows that she does not carry the rare high-risk BRCA1 and BRCA2 alleles. What if further testing showed that some of her aunts, her mother, and she carried a common low-risk allele for breast cancer. What would you recommend to Julie if you were her genetic counselor?
A man with X-linked color blindness marries a woman with no history of color blindness in her family. The daughter of this couple marries a normal man, and their daughter also marries a normal man. What is the chance that this last couple will have a child with color blindness? If this couple has already had a child with color blindness, what is the chance that their next child will be color blind?
What causes most of the phenotypic abnormalities in someone with Down's Syndrome? A) They have many gene mutations that produce nonfunctional proteins. B) They express too much of some proteins during development. C) Their cells cannot go through mitosis properly during development because they have an odd number of chromosomes. D) Their chromosomes cannot pair during meiosis.
Hereditary hemochromatosis is an autosomal recessive genetic disorder that causes the body to absorb too much iron from the diet. This excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. Q. A man who had hemophilia (an X-linked recessive genetic disorder), married a woman who had no family history of hemophilia whatsoever. The couple had consulted a genetic counselor when they first contemplated having children due to concerns that their future children might have hemophilia. Genetic testing of both future parents revealed that the husband did, in fact, possess the Hemophilia A allele but his wife was completely normal with respect to hemophilia. Much to their shock, their first child, a daughter, had a mild blood clotting disorder. Karyotyping was performed to determine whether this daughter had an…