Let’s say that a large ancestral population of really cool organisms is subdivided, by a geological cataclysm, into a large number of isolated, ideal populations, each of size 100. Suppose we’re interested in an autosomal locus with two alleles, A and a, with p = the frequency of A = 0.75 in the ancestral population, as well as in each newly isolated population. Assume that genetic drift is the only evolutionary force operating. a) What is the average allele frequency of A in the populations after 5, 10, and 100 generations? b) What allele frequencies of A do you expect to find within each population at equilibrium, and what percentage of the populations will have each specific allele frequency? (recall various simulations we did/could do of genetic drift in several populations)  c) What is the average Inbreeding Coefficient (or Fixation Index) F for each population after 20 generations? Assume F = 0 for all individuals in the ancestral population.  d) Redo (c), assuming an initial allele frequency p = 0.45

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter19: Population Genetics And Human Evolution
Section: Chapter Questions
Problem 7QP: How Can We Measure Allele Frequencies in Populations? Drawing on your newly acquired understanding...
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Let’s say that a large ancestral population of really cool organisms is subdivided, by a geological cataclysm, into a large number of isolated, ideal populations, each of size 100. Suppose we’re interested in an autosomal locus with two alleles, A and a, with p = the frequency of A = 0.75 in the ancestral population, as well as in each newly isolated population. Assume that genetic drift is the only evolutionary force operating.

a) What is the average allele frequency of A in the populations after 5, 10, and 100 generations?

b) What allele frequencies of A do you expect to find within each population at equilibrium, and what percentage of the populations will have each specific allele frequency? (recall various simulations we did/could do of genetic drift in several populations) 

c) What is the average Inbreeding Coefficient (or Fixation Index) F for each population after 20 generations? Assume F = 0 for all individuals in the ancestral population. 

d) Redo (c), assuming an initial allele frequency p = 0.45 

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