Many aspects of gene function can be nicely explained with the one- gene-one-enzyme hypothesis, which states that a gene controls the production of an enzyme. Which of the following findings about gene expression, though, requires an expansion of this simple concept? Non-enzyme proteins are made from genes too. Some genes code for RNA molecules only. Enzymes composed of different polypeptides are coded for by more than one gene. Oa and c, but not b a, b, and c

Many aspects of gene function can be nicely explained with the one- gene-one-enzyme hypothesis, which states that a gene controls the production of an enzyme. Which of the following findings about gene expression, though, requires an expansion of this simple concept? Non-enzyme proteins are made from genes too. Some genes code for RNA molecules only. Enzymes composed of different polypeptides are coded for by more than one gene. Oa and c, but not b a, b, and c

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 10QP: If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense...

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Many aspects of gene function can be nicely explained with the one-gene-one-enzyme hypothesis, which states that a gene controls the production of an enzyme. Which of the following findings about gene expression, though, requires an expansion of this simple concept? Choose an answer below: Non-enzyme proteins are made from genes too. Some genes code for RNA molecules only. Enzymes composed of different polypeptides are coded for by more than one gene. a and c, but not b a, b, and c
In a first attempt to describe the relationship between genes and phenotypes, Beadle and Tatum in the 1940s stated that each gene is a section of the genome that codes for a specific enzyme (one-gene-one-enzyme hypothesis). Which more recent discoveries regarding gene expression are not covered by this hypothesis? Some genes are transcribed into functional RNA molecules that are not translated into protein. Genes code for proteins other than enzymes. Enzymes comprised of several different polypeptides, such as RNA polymerase, are encoded by more than one gene. a and b, but not c a, b, and c
For each element in the list that follows, indicate whatkind of molecule it is (DNA, RNA, protein, smallmolecule), whether it acts as a positive or negativeregulator, what stage of gene expression it affects, andwhether it acts in cis or in trans. (In its most generalsense, the term cis describes elements that affect the function of the molecule of which it is a part, whiletrans describes elements on one molecule that affectthe function of a different molecule.)a. Lac repressorb. lac operatorc. CRPd. CRP-binding sitee. Trp repressorf. charged tRNATrp (in terms of its function at thetrp operon)g. the antiterminator at the trp operonh. a terminator in the expression platform of ariboswitchi. an sRNA that blocks mRNA translation
One mutation is a deletion of six nucleotides in the second exon of the gene and the other mutation is an insertion of two nucleotides in the third intron of the gene. Which is more likely to have a significant effect on the expression of a functional polypeptide from this gene?
What is the name given to study of biochemical nature of genes and how genes express their encoded information
What is dominant control mechanism of gene expression? explain the following image.
Which of the following scenario will result in greater consequences in terms of gene expression? insertion or deletion of one nucleotide insertion or deletion of three nucleotides Explain why.
The following is a list of mutations that have beendiscovered in a gene that has more than 60 exons andencodes a very large protein of 2532 amino acids.Indicate whether or not each mutation could cause adetectable change in the size or the amount of mRNAand/or a detectable change in the size or the amountof the protein product. (Detectable changes in size oramount must be greater than 1% of normal values.)What kind of change would you predict?a. Lys576Val (changes amino acid 576 from lysineinto valine)b. Lys576Argc. AAG576AAA (changes codon 576 from AAG toAAA)d. AAG576UAGe. Met1Arg (at least two possible scenarios exist forthis mutation)f. promoter mutationg. one base pair insertion into codon 1841h. deletion of codon 779i. IVS18DS, G–A, + 1 (this mutation changes thefirst nucleotide in the eighteenth intron of the gene,causing exon 18 to be spliced to exon 20, thusskipping exon 19)j. deletion of the poly-A addition sitek. G-to-A substitution in the 5′ UTRl. insertion of 1000 base…
You are studying a mutation in mice, which acts dominantly. Mice that have only one copy of the allele carrying this mutation have a kinky tail phenotype. You identify the gene that the mutation affects and find that the codon that encodes the second amino acid in the predicted protein has been mutated to a stop codon. Would you characterize this mutation as a loss-of-function or a gain-of-function and what specific subtype (hypermorphic, antimorphic, etc. ) within these categories? Explain your reasoning.”
How might a point mutation in DNA affect the phenotype. How the genome is expressed in the organism? (Please explain this at the molecular level).
Given the following schematic for a gene and its associated regulatory regions, answer the following questions by placing the correct letter in the provided blanks please put in the correct letter for the questions What region would provide cell type-specific expression of genes? region What site would significantly increase gene expression rates? = region What region or regions of this gene’s coding sequence are expressed as amino acids = region
The first product of genome expression is transcriptome but what happens if the RNA of the genes are not activated at a certain time?