Many transcriptional activators are proteins with a DNA-binding domain (DBD) and an activation domain (AD). Explain how each domain contributes to transcriptional initiation. Would you expect repressors to also have each of these domains?

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 21QP: Transcriptional regulators are proteins that bind to promoters (the 5-flanking regions of genes) to...
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Many transcriptional activators are proteins with a DNA-binding
domain (DBD) and an activation domain (AD). Explain how each
domain contributes to transcriptional initiation. Would you
expect repressors to also have each of these domains?

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