Many types of breast cancer have chromosomal translocation mutations. What scenario best describes, what occurs during this type of mutation, causing cells to proliferate abnormally? Chromosomal translocations may place the gene downstream near the promoter region, therefore causing over-expression of the gene The gene may be placed in the transcription start site, downstream of the gene, initiating transcription by recruiting polymerase II Translocation mutations will initiate the transcription of mRNA in the cytoplasm of the cell catalyzing protein synthesis. Chromosomal translocations can sometimes place a gene under the control of a powerful enhancer, upstream.
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Question:-
Many types of breast cancer have chromosomal translocation mutations. What scenario best describes, what occurs during this type of mutation, causing cells to proliferate abnormally?
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Chromosomal translocations may place the gene downstream near the promoter region, therefore causing over-expression of the gene |
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The gene may be placed in the transcription start site, downstream of the gene, initiating transcription by recruiting polymerase II |
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Translocation mutations will initiate the transcription of mRNA in the cytoplasm of the cell catalyzing protein synthesis. |
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Chromosomal translocations can sometimes place a gene under the control of a powerful enhancer, upstream. |
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