Match the region A,B,C. Question 4 Below is the structure of a hypothetical photo-affinity probe analogue of the anti- malarial drug artemisinin: C H H. H HN artemisinin photoaffinity probe Match the regions A, B, and C as indicated in the structure with their role in the photoaffinity labeling experiment Cross-links with nearby proteins in the presence of UV light [ Choose ] Allows for identifying/isolating ("fishing") the protein-probe adduct out of a complex mixture [ Choose ] Non-covalently binds to the same [ Choose ] protein target as artemisinin would have

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter3: Stereoisomerism And Chirality
Section3.8: The Significance Of Chirality In The Biological World
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Match the region A,B,C.
Question 4
Below is the structure of a hypothetical photo-affinity probe analogue of the anti-
malarial drug artemisinin:
H
NH
H'HN-
artemisinin
photoaffinity
be
Match the regions A, B, and C as indicated in the structure with their role in the
photoaffinity labeling experiment
Cross-links with nearby proteins in
the presence of UV light
[ Choose ]
Allows for identifying/isolating
("fishing") the protein-probe adduct
[ Choose ]
out of a complex mixture
Non-covalently binds to the same
[ Choose ]
protein target as artemisinin would
have
>
Transcribed Image Text:Match the region A,B,C. Question 4 Below is the structure of a hypothetical photo-affinity probe analogue of the anti- malarial drug artemisinin: H NH H'HN- artemisinin photoaffinity be Match the regions A, B, and C as indicated in the structure with their role in the photoaffinity labeling experiment Cross-links with nearby proteins in the presence of UV light [ Choose ] Allows for identifying/isolating ("fishing") the protein-probe adduct [ Choose ] out of a complex mixture Non-covalently binds to the same [ Choose ] protein target as artemisinin would have >
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