Meiosis is characterized by the pairing of homologous chromosomes during prophase I. In many species, an elaborate structure called the synaptonemal complex forms between homologues. During this pairing, homologues may exchange chromosomal material at sites called chiasmata. In meiosis I, the homologues separate from each other, reducing the chromosome number to the haploid state (thus the reductive division). It is followed by a second division without replication, during which sister chromatids become separated. The result of meiosis I and II is four haploid cells. If sister chromatids separated at the first division, would meiosis still work?

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
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Problem 19QP: The majority of nondisjunction events leading to Down syndrome are maternal in origin. Based on the...
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Meiosis is characterized by the pairing of homologous
chromosomes during prophase I. In many species, an elaborate
structure called the synaptonemal complex forms between
homologues. During this pairing, homologues may exchange
chromosomal material at sites called chiasmata. In meiosis I, the
homologues separate from each other, reducing the chromosome
number to the haploid state (thus the reductive division). It is
followed by a second division without replication, during which
sister chromatids become separated. The result of meiosis I and II
is four haploid cells.

If sister chromatids separated at the first division, would meiosis still work?

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