Most medically useful antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why would the cytoplasmic membrane (in general) be a poor target for antibacterial medications?
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Most medically useful antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why would the cytoplasmic membrane (in general) be a poor target for antibacterial medications?
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- Most medically useful antibiotics interfere with either peptidogly¬can synthesis or ribosome function. Why would the cytoplasmic membrane be a poor target for antibacterial medications?Most medically useful antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why would the cell membrane be a poor target for antimicrobial medication?Some antibiotics target peptidoglycan synthesis. What is amolecular growth target of an antibiotic that inhibitspeptidoglycan synthesis?
- For any antibiotic compounds that don’t appear to inhibit translation of proteins from the ribosome, purpose another potential mechanism whereby this class of antibiotic might be able to act (outside of cell wall/membrane formation). Explain in deatil.Antibiotics that target the cell wall have no effect on the existing peptidoglycan. So how does the antibiotic affect bacterial cells so that the cell walls become weak and the cell lyses?What part of a eukaryotic cell could be affected by antibiotics that target ribosomes and why?
- What implications does the complex hydrophobic mycobacterial cell wall have in terms of treating diseases caused by these bacteria?why is peptidoglycan synthesis inportant in antibiotic activity? why do antibiotics not interfere with cell wall synthesis in the host cells?What kind of enzymatic activities are required to grow the peptidoglycan cell wall?
- Antibiotic medication work by targeting specific structures and function in bacterial cells. Side effects in the patient are usually minimal, because their eukaryotic cells do not possess the same structures and characteristics as the prokaryotic pathogens. What structures or functions of the prokaryotic cell would serve as good targets for new antibiotics?E. coli cells have peritrichous flagella. What does this mean?What are the structural reasons for therigidity that is conferred on the cell wall by the peptidoglycan structure?