
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Penicillin is an antibiotic. It kills bacteria by preventing the formation of the peptidoglycan layer of the bacterial cell wall. Penicillin does so by inhibiting the enzyme Transpeptidase, which is required for peptidoglycan layer formation. What type of inhibitor is Penicillin? Explain.
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- A young student is troubled by the idea that a bacterium is able to control its diverse and complex metabolic activities, even though it lacks a brain. How would you explain their metabolic control?arrow_forwardBeta lactam antibiotics disrupt peptidoglycan synthesis by binding to the bacterial enzyme necessary for peptide bond formation between TPCS of different PG layers.arrow_forwardThe following are methods to control for bias during data collection, except: a. Assuring subjects' anonymity and confidentiality b. Reducing the number of participants c. Providing training for interviewers d. Randomly assigning subjects to experimental/controlarrow_forward
- Penicillin does not directly kill bacteria. Why, then is it considered to be bacteriocidal?arrow_forwarda) bacteria are “obligate anaerobes.” What does this mean? On Earth, where might these organisms live? (Give examples.) b) Humans (and most Eukaryotic organisms) are obligate aerobes. What does this mean? On Earth, where might these organisms live? (Give examples.)arrow_forwardOne approach to combat drug resistance in bacteria is to combine drugs to treat bacterial infections. For example, ampicillin, a beta-lactam antibiotic, is combined with clavulanic acid, a beta-lactamase inhibitor. Describe how these two drugs would act together to be more effective to treat a bacterial infection.arrow_forward
- Explain how bacteria can become resistant to ampicillin. Be sure to mention the following terms: peptidoglycan, beta lactamase, transpeptidase, beta lactam.arrow_forwardMost of the micronutrients are transition elements. What property of the transition elements makes them especially suitable for their roles in the body?arrow_forwardWhy is peptidoglycan such a strong molecule?arrow_forward
- How would cellulose-degrading bacteria in the rumen of a cow benefit the animal?arrow_forwardWhat molecule does Penicillin G inhibit?arrow_forwardWhich ONE of the following best describes amoxicillin? Select one: A. A natural product produced by Streptomyces spp. B. Suitable for use alone against beta-lactamase-producing bacteria C. Inhibits the transglycosylation step in peptidoglycan synthesis D. The presence of an amino group facilitates entry through water-filled porins within the outer membrane of E. coli E. Is classified as a carbapenemarrow_forward
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