Most people with the dominant mutant polydactyly allele have extra digits but at least 25% have the normal number of digits. What is the genetic explanation for this observation?
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Most people with the dominant mutant polydactyly allele have extra digits but at least 25% have the normal number of digits. What is the genetic explanation for this observation?
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- What is the Dominant and Recessive allele of the Double Muscling phenotype of a Belgian Blue beef cattle?The genotype of EB27 and EB67 are unknown. Based on pedigree, what are the most likely genotype of each individual?In crosses between mutant mice, you find the following patterns in the genotype for the A locus containing alleles A1, A2, A3 and A4: What would be the best explanation for the inheritance and why?
- Can the genotype of a black fur mouse be determined? Why or why not?This pedigree traces the inheritance of a trait in humans. Based on this pedigree, is the allele for this disease dominant or recessive? Is it sex-linked? Explain. What genotypes are most probable for the individuals labeled 4, 7, and 10?Given that the mutation causing deafness in the family shown in Figure 19–26 is very rare, what is the most probable genotype of each of the four children in generation II?
- In a particular country in sub-Saharan Africa, a medical study revealed that 0.075% of the country's population are suffering from sickle-cell anemia. Sickle cell disease is caused by a mutation in the haemoglobin-Beta gene found on chromosome 11. Sickle cell anemia is controlled by a pair of alleles, H and h, where the individuals with the illness have the homozygous recessive genotype; those with normal red blood cells have the alternative genotype. Using the Hardy-Weinberg's equation, calculate the percentage of the population of the two genotypes for normal blood cells. In a few remote areas in that country, the percentage of sickle cell anemia reaches as high as 5%. Calculate the percentage of homozygous and heterozygous individuals with the normal blood cells and find the ratio for both phenotypes.If a male bird that is heterozygous for a recessive Z-linked mutation is crossed to a wild type female, what proportion of the progeny will be mutant males?What are Possible Dominance Relations in case of neomorphic mutations?
- What is the term for situations in which a single functional allele of a gene is unable to mask an allele that deletes the gene completely?Imagine that individual V-8 marries a female cousin who is a carrier of the 5αRD mutation. What is the probability that they will have a child who has the disorder? answer should be a fraction.What are Possible Dominance Relations in case of hypomorphic mutations?