New drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups from histone proteins. Explain how these drugs could affect gene expression to help kill tumor cells.

Q: Enzymes that phosphorylate proteins is an example of gene regulation by ---- "

A: Ans. The charged and hydrophilic group of Phosphorylation is inserted into the amino acids side…

Q: A researcher found that she could increase phosphorylation of amino acids adjacent to methylated…

A: Histone Phosphorylation It is associated with transcriptional activation.  It takes place with the…

Q: How does an intracellular receptor regulate gene expression in the cell? Describe briefly what…

A: Intracellular receptors found inside the cell. Typically in the nucleus and cytoplasm. They are…

Q: Translational control of gene expression occurs within thea. nucleus.b. cytoplasm.c. nucleolus.d.…

A: A gene is the fundamental biology unit just like the atom. Gene expression is the process by which…

Q: Would the mutation in the blue protein be considered a enhancer or suppressor of the original…

A: Mutation is an event that is responsible for the change in the nucleotide sequence in the DNA of an…

Q: True or False.  De-acetylation of histone tails allows nucleosomes to pack together into tighter…

A: DNA is the nucleic acids present in the organisms. DNA is the deoxy ribose nucleic acid in which…

Q: compare how histones and micro RNA control gene expression.

A: A gene is an essential unit of heredity and a succession of nucleotides in DNA or RNA that encodes…

Q: A mutation within a gene sequence changes the start codon to a stop codon. How will this mutation…

A: Mutations are changes that occurs in the deoxyribonucleic acid (DNA) sequence, either due to…

Q: Explain how transcription regulators in eukaryotic cells are able to act at a great distance from…

A: DNA is a nucleic acid present in the nucleus of the eukaryotic cells.

Q: Explain the steps in Histone Modification in the process of Phosphorylation. Take note, important…

A: Histones are proteins that associate with DNA to help in the condensation into chromatin. They are…

Q: Describe the ways in which gene expression is regulated Must include: • Transcription factors •…

A: Transcription factors and Histone acetylation favors gene expression and DNA methylation represses…

Q: Some hormones act by binding to the promoters of particular genes in such a way that RNA polymerase…

A: Hormones are the organic substances that are produced in small amounts by specific glands, which are…

Q: The addition or deletion of methyl and acetyl groups to regulate transcription Proteins that…

A: Answer. Transcription is a process of formation of transcript (RNA). It takes place by the usual…

Q: Suppose that a mutation in the glucocorticoid receptor does not prevent the binding of the…

A: A glucocorticoid receptor is a receptor of cytosols and other glucocorticoids. It regulates the…

Q: Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels…

A: Given, X is a cancer cell line which was treated with a drug Y. It resulted in the increase of…

Q: Cancer cells removed from a patient's tumor have increased gene expression of several hundred genes…

A: Cancer  Cancer if a kind of disorder which caused by several means like drug, radiation, malfunction…

Q: Epigenetic control of gene expressiona. is hereditary. c. adds methyl groups to cytosine.b. locks…

A: Stem cells are cells that can grow not other cells in the body. Stem cells are of two types one is…

Q: Explain why cells need to control gene expression.

A: Gene expression is the process in which the functional gene is produced by the gene containing…

Q: Histone modifying enzymes can be over- or under-expressed in a variety of human diseases and…

A: According to guidelines we have to answer the first question only. so please kindly post the…

Q: Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels…

A: The genes that suppress tumors are ordinary genes, which delay cell division, fix DNA errors or tell…

Q: Discuss histone remodeling and its effect on transcription.

A: Histone-modifying complexes are protein complexes that catalyse the addition or removal of different…

Q: Mention the function of non-histone protein.

A: The chromosomes are thread-like structure located in the nuclei of both plant and animal cells. They…

Q: Enzymes that acetylate the e-amino group of lysine in the histone tails are called and are involved…

A: Histone is made up of majority lysine and arginine (positive amino acids) as a result negative…

Q: What is cell differentiation? Discuss the role of myogenic bHLH proteins in the differentiation of…

A: Proteins are the building blocks of the body and they are composed of chains of amino acids. Amino…

Q: Define the following terms: a. epigenetics b. CpG island c. epimutation d. DNA methylation e.…

A: Definitions are explained.

Q: Explain why a loss or an excess in genetic material leads to the expression of an abnormal

A: Introduction :- Mutations are changes in a gene's DNA that are abnormal. Bases are the basic…

Q: Please explain correct answer

A: Apoptosis is an energy dependent genetically programmed process which occurs during embryogenesis,…

Q: Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels…

A: Cancer cell lines are usually generated by isolating them from the cancer tissue itself. These cells…

Q: Which of the following mode of gene regulation CANNOT be regarded as "transcriptional regulation"…

A:

Q: Sometimes a transcription factor within the cytoplasm can act as an intracellular receptor for a…

A: Transcription factors are the proteins that help in recognizing the promoter region of a gene and…

Q: The tumor suppressor pRB also binds to and suppresses the activity of retinoblastoma-binding protein…

A: Mutation in genes is the process of change in the nucleotide sequence of the genome.

Q: Explain Termination of transcription by rho specific protein

A: The Rho factor is a protein that  is involved in termination of transcription in prokaryotes. Rho…

Q: Under normal physiological conditions, proto-oncogenes and tumor suppressors help control cell…

A: A significant contrast among the oncogenes and tumor suppressor genes is that oncogenes result from…

Q: Which illustration below correctly depicts the effect of histone modification in chromatin…

A: The power of ATP is used by chromatin remodelers to move DNA around nucleosomes. Remodeler…

Q: Histones can be modified to turn genes on and off. Which type of chromatin is associated with…

A: Chromatin is a complex form of DNA  molecule and  Histone protein which was found in eukaryotic…

Q: Suppose a chemist develops a new drug that neutralizes the positive charges on the tails of histone…

A: Nucleosome is a basic structural and functional repeating unit of chromatin. It is also a unit of…

Q: Please answer all questions if possible.  -B-Raf is not overexpressed in cancer though shows…

A: B raf is a protooncogene that produce BRaf protein. This protein plays role in regulating MAP…

Q: TRUE OR FALSE Errors in transcription can lead to silent mutations encoding the same amino acid or…

A: Silent mutations are the type of mutations in which base substitution has no effect in…

Q: Which of the following will lead to a decrease in transcription of a gene? O A. Increase in histone…

A: Decrease in DNA methyltransferases.

Q: Cancer cells often have abnormal patterns of chromatin modifications. In some cancers, the DNA…

A: Cancer is a metabolic disorder characterized by abnormal cell growth. Cancerous growth of tissues…

Q: Gene expression in mammals can be increased by which of the following mechanisms?…

A: Nucleosome is the packaging unit in eukaryotes. It is a fundamental subunit of chromatin.…

Q: New drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups…

A: Gene expression is the process by which the informations contained in the DNA becomes functional in…

Q: Refer to the following illustration to answer the question. O protein A is not made because it is…

A: There are some substances (protein, carbohydrate etc) which regulates the expression of genes. For…

Q: eritable effects of gene expression that are not caused by a change in DNA sequence are called…

A: EPIGENETIC CHANGES are heritable changes in gene expression that do not involve changes to the…

Q: Chromatin remodeling is linked to epigenetics.  Explain how this works and indicate the driving…

A: Epigenetics is referred to as the study of phenotype changes that are inheritable and does not…

Q: how would the disruption of the Rb family of proteins lead to cancer? Describe the possible…

A: Please follow step 2 for detailed explanation.

Q: The tumor suppressor pRB also binds to and suppresses theactivity of retinoblastoma binding protein…

A: The segments of the genetic material which helps in the expression of the characters are known as…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.