Tumor-suppression g x code for a variety of proteins that regulate the cell cycle to inhibit proliferation or induce apoptosis. [Three words.)

Q: 36. After DNA damage (e.g. caused by X-ray exposure) in eukaryotic cells, the cell cycle can be…

A: Cell cycle checkpoints are present to ensure that the damaged or incomplete chromosomes do not under…

Q: directly to DNA and plays a critical role in determining whether the DNA will be repaired or the…

A: p53 Mutations are a Frequent Event in Cancer:--The evolution in a normal cell producing cancerous…

Q: TRUE or FALSE [For extra credit, correct False statements] a. Proteins that lack a sorting signal…

A: Signal sequence are the sorting signals that direct the protein to the secretory pathway in…

Q: QUESTION 2 p53 is a multifunctional protein. Select the domain, if any, that contains the most -…

A: p53 protein :-

Q: Occurred in her cells? (Unfortunately her parents have passed away.) I think these genes are…

A: CRISPR stands for Clustered regularly interspaced short palindromic repeats. It is a system of…

Q: a. A typical cellular response of a mammary epithelial cell to EGF signal is proliferation. the Kd…

A: Proliferation is the cellular response.

Q: To explain: How the low pH of lysosomes protect the rest of the cell from lysosomal enzymes in case…

A: Many metabolic pathways exist in the human body to maintain homeostasis. Many chemical reactions…

Q: Virtually all cancer treatments are designed to killcancer cells, usually by inducing apoptosis.…

A: Acute Promyelocytic Leukemia (APL or APML) is a cancer of the white blood corpuscles. Abnormal…

Q: The drug vincristine, which prevents polymerization of tubulin, is used as a chemotherapeutic agent…

A: Vincristine is a chemotherapeutic medication that belongs to the vinca alkaloids family of…

Q: The retinoblastoma tumor suppressor gene Rb (RB1) codes forthe retinoblastoma protein (pRB). pRB…

A: Retinoblastoma is a tumor suppressor gene during cancer progression, loss of function of tumor…

Q: Give the pathway-disruption in the pathway of apoptosis, how this can lead to different diseases?

A: Apoptosis is a process in which cell is directed to death. They could be done by intrensic and…

Q: Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels…

A: Given, X is a cancer cell line which was treated with a drug Y. It resulted in the increase of…

Q: 45. Receptor tyrosine kinases (RTK)s are the high-affinity cell surface receptors for many…

A: The correct statements are: Option d. Only A, B and D.

Q: (a) Write a possible sequence for an mRNA segment coding for apamine.(b) Do you think apamine is…

A: Introduction: mRNA synthesizes from the copies of DNA by the process known as transcription.

Q: Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels…

A: The genes that suppress tumors are ordinary genes, which delay cell division, fix DNA errors or tell…

Q: Certain types of cancerous lung tumors can secrete hormones normally made by the pancreas, adrenal…

A: Lung neoplasms are a form of cancer that occurs in the lung cells most likely in individuals who…

Q: Protein P, normally stimulates apoptosis or cell death when activated. Consider a cell with a…

A: The construction of this question gives us an  information about the nature of protein P, P when…

Q: how would an inactive complex 1 lead to cell damage and cell death as seen in Parkinson’s patients ?

A: Inactive complex 1 can lead to formation of Reactive Oxidative species(ROS) and also reduces…

Q: During apoptosis, phosphatidylserine undergoes transverse movement (flip-flop). Explain why this…

A: The programmed cell death is also known as apoptosis. The apoptosis process includes phagocytic…

Q: Cell division cycle mutations render the mutants unable to continue the cell cycle. This…

A: Cellular checkpoint prevents the progression of cell cycle if the cell is unfavorable (such as…

Q: Explain how can you  study protein Z components? (needed)

A: The proteins are the macromolecules and these structures are so so small that they can be seen by a…

Q: Some transcription factors contain bromodomains. Explain the function of the bromodomain?

A: Transcription factors are responsible for intiating the transcription process. The transcript…

Q: A cell collected from the stratum germinativum layer of the skin during adulthood might best be…

A: Stem cells are special human cells that are able to develop into many different cell types. On the…

Q: Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels…

A: Cancer cell lines are usually generated by isolating them from the cancer tissue itself. These cells…

Q: This is expressed as the phospholipid flips out during apoptosis     phosphatidylserine…

A: Apoptosis is a type of planned cell death. Cell death and biochemical alterations are the results of…

Q: Cleavage Ligand Precursor Receptor Inactive Receptor Active www 99 Cell Membrane 6. The figure above…

A: In case of hydrophilic signalling molecules (ligand), they binds with specific transmembrane…

Q: T7-MDM2 Myc-RYBP p53-(His-Ub), MDM2 p53 Myc-RYBP B-Actin QUESTION 12 In the RYBP case study paper,…

A: *Ring1 and YY1 binding protein (RYBP) belongs to polycomb group proteins that implicated in…

Q: 8) Indicate which of the five major types of membrane protein (adhesion, enzymatic, recognition,…

A: 1st Ans:  Transmembrane protein

Q: 36- . Proteins acting as a molecular switch fall mostly in two classes; and a) Nuclease - Ligases b)…

A: A molecular switch is known as a molecule that has the ability to get shifted reversibly between two…

Q: The tumor suppressor pRB also binds to and suppresses the activity of retinoblastoma-binding protein…

A: Mutation in genes is the process of change in the nucleotide sequence of the genome.

Q: Cancer cells treated with vitamin E succinate are generally more vulnerable to rupture of their…

A: Cancer is the uncontrolled growth of abnormal cells in a body. Cancer arises as a result of…

Q: Explain why the RTK signaling pathway includes the extra complication of having a protein (Ras) that…

A: Ras is a tiny GTP-binding protein that is part of the signal transduction pathway that growth…

Q: 8. Describe the MAP kinase activation pathway

A: Protein kinases and other messenger systems form highly interactive networks to achieve the…

Q: Why do cancer cells treated with vitamin E succinate appear to be more vulnerable to rupture of…

A: A normal cell undergoes regulated division, differentiation and apoptosis or programmed cell…

Q: Not all genes encoded in the DNA are transcribed into RNA or translated into protein. Explain how…

A: The sequence of DNA in between exons that is initially copied into RNA but is cut out of the final…

Q: Under normal physiological conditions, proto-oncogenes and tumor suppressors help control cell…

A: A significant contrast among the oncogenes and tumor suppressor genes is that oncogenes result from…

Q: 14. An example of hematopoietic cells. - O Living cells O Adherent cells O Stem cells O Suspension…

A: Introduction :- All of the cellular components of blood and blood plasma are created during…

Q: In a given sample (whole organism, tissue, cell, subcellular compartment), what fraction of the…

A: Biological processes require several different macromolecules for their metabolic and functional…

Q: 21. Which of the following molecules is NOT involved in cell-to-cell signaling? A. prostaglandins…

A: Cell signaling is a process, which helps cells release chemical signal molecules that help to…

Q: Effects of BPA on phosphorylation of MAPK family in RAW264.7 cells conclusion

A: Bisphenol A or BPA is one of the key component of polycarbonate plastics and it causes a wide range…

Q: Increased stability of, would lead to low G1/S-Cdk activity. Select one: O a. Cdc20 O b. Wee1 О с.…

A: The G1/S transition is highly regulated by transcription factor p53 in order to halt the cell cycle…

Q: Apoptosis-inducing activity of a fluorescent barrel rosette M+ /Clchannel“.The whole process…

A: Apoptosis is a type of cell death programmed or cell suicide, that is different from necrosis in…

Q: Comparing cells synthesizing secretory proteins and cells secreting steroid hormones, the cells…

A: Mitochondria are the sites where steroid hormone synthesis takes place.

Q: Also explain why this enzyme does not break down proteins on its way to the lysosome but becomes…

A: Lysosome. A lysosome is a membrane-bound cell organelle that contains digestive enzymes. ... They…

Q: 98. The correct sequence of cell signaling is

A: Cell signaling can be defined as a part of the communication process governing the basic activities…

Q: Alterations in cellular and organellar phospholipid compositions of HepG2 cells during cell growth

A: Hepatoblastoma cell Liver cancer is the 7th most commonly diagnosed cancer and the third leading…

Q: Embryonic stem cells are and adult stem cells are multipotent; pluripotent pluripotent; multipotent…

A: Option b  Pluripotent and multipotent

Q: 4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized…

A: intracellular signaling is an important function . these are mediated via receptors on the cell…

Clinical Pharmacology

Pharmacology is a discipline of medicine that studies how medications interact with the systems and processes of living organisms, focusing on drug action mechanisms as well as therapeutic and other purposes.