NH NH pyrrole pKa = 23 pyrrolidine pka = 44

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins
Section26.2: Amino Acids And The Henderson–hasselbalch Equation: Isoelectric Points
Problem 4P: Hemoglobin has pI=6.8. Does hemoglobin have a net negative charge or net positive charge at pH=5.3?...
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Why is pyrrole more acidic than pyrrolidine?

NH
NH
pyrrole
pKa = 23
pyrrolidine
pka = 44
Transcribed Image Text:NH NH pyrrole pKa = 23 pyrrolidine pka = 44
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