No lactose in the cell The repressor binds to operator, blocking transcription. lacY (permease) lacA lacZ (B-galactosidase) (transacetylase) DNA Terminator RNA polymerase bound to promoter to operator Repressor bound Lactose present in the cell Some lactose is converted to allolactose. This binds to the repressor and alters its shape, so that it can no longer bind to the operator. If glucose is not available, the operon will be transcribed. Transcription Transcription O FIGURE 7.23 Lactose and the lac Operon B-Galactosidease is the enzyme that hydrolyzes lactose into its monosaccharide components. Allolactose Non-functional repressor Permease is the transporter that brings Translation lactose into the cell. The function of transacetylase in lactose catabolism is not fully understood. ? When would the lac operon in E. coli be repressed, and why?

Biology: The Dynamic Science (MindTap Course List)
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Chapter16: Regulation Of Gene Expression
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When would the lac operon in E. coli be repressed, and why?

No lactose in the cell
The repressor binds to operator, blocking transcription.
lacY
(permease)
lacA
lacZ
(B-galactosidase)
(transacetylase)
DNA
Terminator
RNA polymerase
bound to promoter to operator
Repressor bound
Lactose present in the cell
Some lactose is converted to allolactose. This binds to
the repressor and alters its shape, so that it can no
longer bind to the operator. If glucose is not available,
the operon will be transcribed.
Transcription
Transcription
O FIGURE 7.23 Lactose and the
lac Operon B-Galactosidease is the
enzyme that hydrolyzes lactose into its
monosaccharide components.
Allolactose
Non-functional
repressor
Permease is the transporter that brings
Translation
lactose into the cell. The function of
transacetylase in lactose catabolism is
not fully understood.
? When would the lac operon in E. coli be
repressed, and why?
Transcribed Image Text:No lactose in the cell The repressor binds to operator, blocking transcription. lacY (permease) lacA lacZ (B-galactosidase) (transacetylase) DNA Terminator RNA polymerase bound to promoter to operator Repressor bound Lactose present in the cell Some lactose is converted to allolactose. This binds to the repressor and alters its shape, so that it can no longer bind to the operator. If glucose is not available, the operon will be transcribed. Transcription Transcription O FIGURE 7.23 Lactose and the lac Operon B-Galactosidease is the enzyme that hydrolyzes lactose into its monosaccharide components. Allolactose Non-functional repressor Permease is the transporter that brings Translation lactose into the cell. The function of transacetylase in lactose catabolism is not fully understood. ? When would the lac operon in E. coli be repressed, and why?
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