Now talk about how it affects newly synthesized proteins, SUMOylation impacts protein and protein interactions. It impact assembly of multiprotein complexes too. The cellular processes that regulated by it include DNA damage response a cell cycle progression or the control of gene expression.
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- Some proteins are shuttled back and forth between the nucleus and the cytoplasm. How do you think this is possible? (Hint: the protein must have 2 things)Cancer cells treated with vitamin E succinate are generally more vulnerable to rupture of their lysosomal membranes (and subsequent apoptosis) than are normal cells, because: cancer cells often have an acidic cytosol, and their lysosomes have an acidic pH too cancer cells often have an acidic cytosol, but their lysosomes have an alkaline pH cancer cells often have an alkaline cytosol, and their lysosomes have an alkaline pH too cancer cells often have an alkaline cytosol, but their lysosomes have an acidic pH all of the aboveSelect the true statements regarding the control of proteins in the cell. Sequestering of proteins in lysozomes is common in cells that function to secrete singaling molecules. Access to monomers is a method of controling polymer synthesis used in the cell post-translation. Phosphorylation involves post-translational control of protein shape and therefore activity. Allosteric activation of proteins is a form of pre-translational control.
- Phosphorylation of nuclear lamins regulates their assembly and disassembly during mitosis. You add a drug to cells that are undergoing mitosis that inhibits the activity of an enzyme that dephosphorylates nuclear lamins. What do you predict will happen to these cells? Why?Glycophorins are a type of membrane protein found on red blood cells. They allow red blood cells to circulate through the blood vessels without sticking to the walls of the blood vessels or to other cells. Describe how a glycophorin protein would be synthesized by the cell. Include What parts of the cell are involved and what happens at each location. The process of protein synthesis (i.e. transcription, translation, etc).In the ER lumen nascent polypeptide chains are kept from misfolding or aggregating until an entire domain or polypeptide is completed and can fold properly. true false
- Describe the order of organelles needed to produce and distribute a protein. Make sure to explain what each organelle is doing for that protein.The compartmentalization (division) of eukaryotic cells allows many processes to function properly. Summarize how proteins based on peroxisomal proteins get to the right place.Why do cancer cells treated with vitamin E succinate appear to be more vulnerable to rupture of their lysosomal membranes (and subsequent apoptosis) than normal cells? cancer cells often have an alkaline cytosol, which destabilizes the alkaline lysosomes cancer cells often have an alkaline cytosol, which destabilizes the acidic lysosomes cancer cells often have an acidic cytosol, which destabilizes the alkaline lysosomes D. cancer cells often have an acidic cytosol, which destabilizes the acidic lysosomes all of the above
- I am having trouble with this part of my homework. The integral membrane protein XYZR has a single alpha helix spanning the membrane. Where was this protein made and what can you say about amino acids that occur/do not occur in the alpha helix versus the domains sticking out on both sides of the membrane?Cell division cycle mutations render the mutants unable to continue the cell cycle. This phenotype creates a paradox where mutant cells must also be grown in the lab to further identify the gene and study the role of the protein. How do you think this problem can be solved?Protein synthesis occurs in all living cells. Why, then, are some antimicrobial drugs that target protein synthesis selectively toxic to bacteria? The protein synthesis in human cells will only occur inside the nucleus. The ribosomes found in human cells and those found in bacterial cells have different structures. Protein synthesis in bacteria is completed by ribosomes, while protein synthesis in humans is completed by polymerase enzymes. The protein synthesis in human cells occurs less frequently than that in bacterial cells.