Of the following, which should NOT occur in order to facilitate T-cell selection in the thymus? A) positive-selection based on an interaction with MHC alone B) negative-selection based on a failed interaction with self-peptides in a MHC C) apoptosis of T-cells that fail to interact with MHC alone during positive selection. D) negative-selection based on an interaction with MHC containing a non-self peptide

Of the following, which should NOT occur in order to facilitate T-cell selection in the thymus? A) positive-selection based on an interaction with MHC alone B) negative-selection based on a failed interaction with self-peptides in a MHC C) apoptosis of T-cells that fail to interact with MHC alone during positive selection. D) negative-selection based on an interaction with MHC containing a non-self peptide

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter9: Immunity And Disease

Section: Chapter Questions

Problem 4RQ: What is the difference between an allergy and an autoimmune response?

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Similar questions

What is the difference between a T-cell-dependent and T-cell- independent response?
How is the newly emerging repertoire of T cells, with their diverse pre-TCRs, further differentiated so that a productive interaction with self-MHC–peptide complexes can occur?
Which of the following statements regarding T cells activated by specific antigen is incorrect? a. They receive co-stimulatory signals through CD28. b. They suppress expression of sphingosine 1-phosphate (SIP). c. They take several days before differentiating into effector T cells. d. They cease to secrete and respond to interleukin-2 (IL-2). e. They begin to express CTLA4, which serves to limit T-cell proliferation.
How can an extracellular bacterium and an intracellular virus independently be targeted by a particular T cell response? And what is the mechanism of antigen presentation?
What distinguishes MHC I from MHC II? a-aquisition of antigenic peptide in the cytoplasm b-cross-presentation of antigegn to CD4 T cells c- presentation of peptides to the T cell receptor d-binding of a B-amino acid peptide e- presentation of antigenic peptides to CD4 T cells
Many cells in the human body have proteins on the surface that are able to interact with the receptors of helper T cells. Explain the mechanisms and why it is that such an interaction or signal does not usually result in an autoimmune reaction?
Which of the following is TRUE regarding Gram negative bacteria? a- Their cell wall is composed of a large proportion of sugars b- Their cell wall does not absorb the Gram stain and turns pink c- Their cell wall is composed of a small proportion of peptidoglycan d- Two of the above statements are true Which T-lymphocytes activate the B-cell response? 1- suppressor T-cells. 2- cytotoxic T-cells. 3- helper T-cells. 4- memory T-cells. Substances that are injected containing an antigen to stimulate the immune system to respond are called a- antibodies b- medications. c- vaccines d- antibiotics
Generally speaking, what kinds of cells express MHC I, MHC II, or both? What is presented on MHC I and II, and what kind of T cell recognizes each one? What response occurs when a T cell recognizes what is being presented on MHC I? What happens if it recognizes MHC II? Give an example of each type of recognition.
All of the following are true in reference to T-cell priming except _____. a. it occurs in primary lymphoid organs b. it transforms naive T cells into differentiated effector T cells c. it is the first stage of a primary adaptive immune response d. it requires interaction between naive T cells and antigen-presenting cells e. it takes place in many locations including, but not limited to, lymph nodes, Peyer’s patches, and the tonsils.
All of the following are characteristic of regulatory T cells except a. they express CD25 b. they facilitate the proliferation of naive T cells interacting with the same antigen-presenting cell c. they express CD4 d. they express the transcriptional repressor FoxP3 e. they express MHC class II-restricted T-cell receptors specific for self antigen.
Why is the response to T-independent antigens important medically?
What is the difference between an allergy and an autoimmune response?