OH CH,OH H НО H CH,OH UDP-galactose-4-epimerase НО НО 0-UDP 0-UDP HO UDP-galactose OH UDP-glucose

General, Organic, and Biological Chemistry
7th Edition
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:H. Stephen Stoker
Chapter18: Carbohydrates
Section: Chapter Questions
Problem 18.119EP
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UDP-galactose-4-epimerase converts UDP-galactose to UDP-glucose. The reaction requires NAD+ as a coenzyme.

a. Propose a mechanism for the reaction.            b. Why is the enzyme called an epimerase?

OH
CH,OH
H
НО
H
CH,OH
UDP-galactose-4-epimerase
НО
НО
0-UDP
0-UDP
HO
UDP-galactose
OH
UDP-glucose
Transcribed Image Text:OH CH,OH H НО H CH,OH UDP-galactose-4-epimerase НО НО 0-UDP 0-UDP HO UDP-galactose OH UDP-glucose
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