он но Он several steps NaHCO, iodolactonization но но но OCH3 в ÓCH3 Он PGF

Chemistry: Matter and Change
1st Edition
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Chapter22: Substituted Hydrocarbons And Their Reactions
Section: Chapter Questions
Problem 48A
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Lactones, cyclic esters such as compound A, are prepared by halolactonization, an addition reaction to an alkene. For example, iodolactonization of B forms lactone C, a key intermediate in the synthesis of prostaglandin PGF2α (Section 4.15). Draw a stepwise mechanism for this addition reaction.

он
но
Он
several steps
NaHCO,
iodolactonization
но
но
но
OCH3
в
ÓCH3
Он
PGF
Transcribed Image Text:он но Он several steps NaHCO, iodolactonization но но но OCH3 в ÓCH3 Он PGF
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