One of the following is a characteristic of eukaryotic genetic material? 1. Eukaryotic genetic material is compacted by wrapping the double-helix around histone proteins to form nucleosomes. 2. Eukaryotic genetic material consists of supercoiled circular DNA molecules complexed with proteins into chromosomes. 3. Eukaryotic genetic material consists of relaxed linear DNA molecules complexed with RNA into a 30 nm fiber. 4. Eukaryotic genetic material is compacted by folding linker regions around non-histone proteins to form a scaffold.

One of the following is a characteristic of eukaryotic genetic material? 1. Eukaryotic genetic material is compacted by wrapping the double-helix around histone proteins to form nucleosomes. 2. Eukaryotic genetic material consists of supercoiled circular DNA molecules complexed with proteins into chromosomes. 3. Eukaryotic genetic material consists of relaxed linear DNA molecules complexed with RNA into a 30 nm fiber. 4. Eukaryotic genetic material is compacted by folding linker regions around non-histone proteins to form a scaffold.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter15: Genomes And Genomics

Section: Chapter Questions

Problem 11QP: When the human genome sequence was finally completed, scientists were surprised to discover that the...

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A diploid human cell contains approximately 6.4 billion base pairs of DNA. Assuming that the linker DNA encompasses 35 bp, how many nucleosomes are present in such a cell? Use two significant figures. How many histone proteins are complexed with this DNA? use two significant figures.
The human genome contains 3 billion nucleotides arranged in a vast array of sequences. What is the minimum length of a DNA sequence that will, in all probability, appear only once in the human genome? You need consider only one strand and may assume that all four nucleotides have the same probability of appearance.
The double helical structure of DNA is intrinsically unstable and easily dissociates to form two separate strands. Why? How does this affect the two key biological functions of chromosomal DNA? What would happen if the DNA helices were too stable?
The average human chromosome contains about 1 x 108 bp of DNA.(a) If each base pair has a mass of about 660 daltons and there are about 2 g of protein (histones plus nonhistones) per gram of DNA, how much doessuch a chromosome weigh (in grams)?(b) If the DNA were extended, how long would it be?(c) An actual chromosome is about 5 mm long. What is the approximatecompaction ratio?(d) You have about 4 x 1012 cells in your body. If you have 46 chromosomes in each cell, what is the approximate extended length of all of your DNA? For comparison, the distance from the earth to the sun isabout 1.5 x 108 km.
. While studying the structure of a small gene that was recently sequenced during the Human Genome Project, an investigator notices that one strand of the DNA molecule contains the following: 20 adenine (A) bases 30 cytosine (C) bases25 guanine (G) bases 22 thymine (T) bases How many of each base is found in the complete double-stranded molecule?
Let’s suppose you have isolated chromatin from some bizarre eukaryote that has a DNA linker region that is usually 300 to 350 bp in length. The nucleosome structure is the same as in other eukaryotes. If you digested this eukaryotic organism’s chromatin with a high concentration of DNase I, what would be your expected results?
If the DNA of one human cell is stretched out, it would be almost 6 feet long and contain over three billion base pairs. How does all this fit into the nucleus of one cell?
To test whether you understand the processes involved in the Central Dogma of Molecular Genetics, determine what amino acid will be formed from the given DNA strand below: #1: 3’ T A C A T G C C G A A T G C C 5’ #2: 3' T A C T G G C A T A A C A C T 5' Note: Prepare the partner strand of the given DNA. Discuss how will replication happen by mentioning the enzyme needed then transcribe to form mRNA. Discuss what will happen to mRNA, then translate, mentioning the anticodon to be used. Look at the genetic code to know what amino acid will become part of the polypeptide chain.
The average human chromosome contains about 1 x 108 bp of DNA. (a) If each base pair has a mass of about 660 daltons and there are about 2 g of protein (histones plus nonhistones) per gram of DNA, how much does such a chromosome weigh (in grams)? (b) If the DNA were extended, how long would it be? (c) An actual chromosome is about 5 mm long. What is the approximate compaction ratio? (d) You have about 4x 1012 cells in your body. If you have 46 chromosomes in each cell, what is the approximate extended length of all of your DNA? For comparison, the distance from the earth to the sun is about 1.5x108 km.
If a human nucleus is 10 mm in diameter, and it must hold as much as 2 m of DNA, which is complexed into nucleosomes that during full extension are 11 nm in diameter, what percentage of the volume of the nucleus is occupied by the genetic material?
The diploid human genome comprises 6,4 * 10^9 bp and fits into a nucleus that is 6 μm in diameter. If base pairs occur at intervals of 0.34 nm along the DNA helix, what is the length of DNA in a human cell If the diameter of the DNA helix is 2,4 nm, what fraction of the volume of the nucleus is occupied by DNA? [volume of a sphere is (4/3)πr^3 and volume of a cylinder is πr^2h]
The analysis of individual nucleosomes reveals that each unit contained one copy of each protein and that the short linker DNA contained no protein bound to it. If the entire chromosome consists of nucleosomes (discounting any linker DNA), how many are there, and how many total proteins are needed to form them?