Pairwise genetic diversity in humans is â = 0.0005/bp and in cockroaches it is ✩ = 0.01/bp. You can assume that the mutation rate is μ = 2 x 10-8/bp/generation in both species. A deleterious mutation with s = 10-6 arises in both humans and cockroaches. A. What is the probability that the allele reaches fixation in humans? Assume it is a new mutation with frequency 1/2N. B. What is the probability that the allele reaches fixation in cockroaches? Assume it is a new mutation with frequency 1/2N. C. Explain in 2-3 sentences why the probability of fixation differs between humans and cockroaches.
Pairwise genetic diversity in humans is â = 0.0005/bp and in cockroaches it is ✩ = 0.01/bp. You can assume that the mutation rate is μ = 2 x 10-8/bp/generation in both species. A deleterious mutation with s = 10-6 arises in both humans and cockroaches. A. What is the probability that the allele reaches fixation in humans? Assume it is a new mutation with frequency 1/2N. B. What is the probability that the allele reaches fixation in cockroaches? Assume it is a new mutation with frequency 1/2N. C. Explain in 2-3 sentences why the probability of fixation differs between humans and cockroaches.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Transcribed Image Text:Pairwise genetic diversity in humans is = 0.0005/bp and in cockroaches it is
✩ = 0.01/bp. You can assume that the mutation rate is μ = 2 x 10-8/bp/generation in
both species. A deleterious mutation with s = 10-6 arises in both humans and
cockroaches.
A. What is the probability that the allele reaches fixation in humans? Assume it is a new
mutation with frequency 1/2N.
B. What is the probability that the allele reaches fixation in cockroaches? Assume it is a
new mutation with frequency 1/2N.
C. Explain in 2-3 sentences why the probability of fixation differs between humans and
cockroaches.
D. What is the probability of fixation of a neutral mutation in humans? What is the
probability of fixation of a neutral mutation in cockroaches?
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