PEDIGREES: Problem 5 (continued) This pedigree shows the inheritance of sickle cell anemia in this family. I QUESTIONS 4. Which individuals in this pedigree have got sickle cell anemia? 1 2 II 2 3 4 5. Is this disease dominant or rec- essive? Explain your reasoning. III 1 2 3 IV 1

PEDIGREES: Problem 5 (continued) This pedigree shows the inheritance of sickle cell anemia in this family. I QUESTIONS 4. Which individuals in this pedigree have got sickle cell anemia? 1 2 II 2 3 4 5. Is this disease dominant or rec- essive? Explain your reasoning. III 1 2 3 IV 1

Name: PEDIGREES: Problem 5 (continued)This pedigree shows the inheritance o
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Description: PEDIGREES: Problem 5 (continued)This pedigree shows the inheritance of sickle cell anemia in this family.• QUESTIONS •4. Which individuals in this pedigreehave got sickle cell anemia?I12II123 45. Is this disease dominant or rec-essive? Explain your

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter17: Genes And The Immune System

Section: Chapter Questions

Problem 17QP

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Instruction - Please answer them correctly - Please answer all of them, they are connected. PEDIGREE ANALYSIS and SYMBOLOGY Examine the pedigree which has X linked Dominant inheritance of disorder. Use letter X* (asterisk denotes disorder) as genotype of the individuals which can be XX, XY, X*X*, X*X and X*Y. a. What is the genotype of IV-6? b. What is the genotype of III-6? c. What is the genotype of II-3? d. What is the genotype of III-8? e. If couple I-1 and I-2 will have a son, what is the probability of having the disorder? f. If couple III-8 and III-9 will have another child, what is the probability of having the disorder? g. Theoretically, if individual IV-3 and individual IV-5 will marry and will have a child, what is the probability of having a child without the X-linked disorder?
Question:- The success of renal transplantation depends on three human histocompatibility genes, HLA-A, HLA-B and HLA-C, which must match between the donor and the receiver. A single mismatch may cause the kidney rejection. Each gene has multiple co-dominant alleles. These three genes are located very close to each other on chromosome 6, so that the recombination rate is very low (below 1%). The father has the following genotype: A1, A2, B24, B10, Cw4 and Cw7 and the mother is A1, A1, B11, B7, Cw5 and Cw8. Their first boy is A1, A1, B24, B11, Cw7 and Cw8. What is the probability that the second child is compatible with his/her brother?
Question A child who is blood type A has a mother who is blood type B. In a paternity suit a man is accused of being the father. He has blood type AB. Is he the father? Yes No He cannot be excluded as the father. There is a 12.5% chance that he is the father. Question If a color-blind female has children, what do we know about all of her sons? It is impossible to know without knowing the father’s genotype. Half of the sons will be color-blind. All sons will have normal color vision. All sons will be color blind. Question What is true about sexual reproduction? Sexual reproduction produces a haploid zygote. Each parent contributes a haploid gene set to offspring. Sexual reproduction consists of mitosis only. Sexual reproduction involves the union of diploid gametes. Question Gametes of the heterogametic sex have different sex chromosomes; gametes of homogametic sex have the same sex…
Codominance: draw a Punnett Square for a AA mom with a AB dad. i. If you have type AB blood type, what possible blood types could your parents have? ii. If you have type A blood, can either of your parents have type O? iii. If you have type O blood, could either of your parents be type AB? Upload your image using the paperclip icon
Practice Pedigree Problem help. I am confused so please show. Label Phenotypes and genotypes as you go about the Pedigree (and whatever else might be required)! Thank you again for your help, these questions confuse me). Hair or fur length in cats is controlled by a single, autosomal gene; the short hair-allele is dominant to the allele for long hair. Hair color is produced by a different gene which is located on the X chromosome. One allele for this sex-linked gene produces yellow, while an alternate allele produces black fur color; individuals which are heterozygous for these alleles are calico or tortiseshell in color. a). If a long-haired, black male is mated with a calico female homozygous for short hair, what kind of kittens will be produced in the F1generation? Give both genotypes and phenotypes; express the genotypes both symbolically and in words.
Two mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?
Ch. 14-9 Mutations in the genes for clotting factor VIII and IX cause hemophilia A and B, respectively. A woman may be heterozygous for mutations in both genes, with a mutated factor VIII allele on one X chromosome, and a mutated factor IX allele on the other. All of her sons should have either hemophilia A or B. However, on rare occasions, one of these women gives birth to a son who does not have hemophilia, and his one X chromosome does not have either mutated allele. Explain.
Question:- Blood typing in human depends on three alleles .The IA and IB alleles are codominant and and the O{i} allele is recessive. An IA IB blood type mother has childern with a B blood type father ( Genotype (IBi). What are the chances that there childern will have AB blood type? a.50% b.100% c.25% d.75% e.0%
8. Secretors (genotypes SS and Ss) secrete their A and Bblood group antigens into their saliva and other bodyfluids, while nonsecretors (ss) do not. What would bethe apparent phenotypic blood group proportionsamong the offspring of an IAIBSs woman and an IAIASs man if typing was done using saliva?
Southern Blotting & Detection of sickle cell disease: Please interrupt the following results and draw a Punnett square, and answer the questions. •Discuss figures (gel figure and Punnett square) one by one. •You must provide discussion for each lane of the gel, how you make out normal, carrier, disease (allelic patterns- why so?), control IMPORTANT POINTS TO REMEMBER: •Homozygous (one band)- the size of the band (lower or higher in the gel) determines if normal (both alleles cut by MSt II, hence band lower) or diseased (both alleles uncut and hence at the higher position in gel) •Heterozygous (two bands in the same lane) denotes a carrier (lower band from normal allele which is cut by RE & upper sickle cell allele band is uncut)
Codominance in blood types. If a male with type A blood (with genotype IAi) mates with a female having type B blood (with genotype IBi), what are the phenotypic ratios for the blood types of the offspring? ___ A : ___ B : ___ AB : ____ O Suppose that one parent has type AB blood, and the blood type of the other parent is not known. Describe how a child can (or cannot) have the following blood types: Type A Type B Type AB Type O
1.ABO blood groups, an autosomal trait, in Humans are genetically determined. A woman with type O blood has a son with type O.