Piebald spotting is a condition found in humans inwhich there are patches of skin that lack pigmentation. The condition results from the inability ofpigment-producing cells to migrate properly duringdevelopment. Two adults with piebald spotting haveone child who has this trait and a second child withnormal skin pigmentation.a. Is the piebald spotting trait dominant or recessive?What information led you to this answer?b. What are the genotypes of the parents?

Piebald spotting is a condition found in humans inwhich there are patches of skin that lack pigmentation. The condition results from the inability ofpigment-producing cells to migrate properly duringdevelopment. Two adults with piebald spotting haveone child who has this trait and a second child withnormal skin pigmentation.a. Is the piebald spotting trait dominant or recessive?What information led you to this answer?b. What are the genotypes of the parents?

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Description: Piebald spotting is a condition found in humans inwhich there are patches of skin that lack pigmentation. The condition results from the inability ofpigment-producing cells to migrate properly duringdevelopment. Two adults with piebald spotting haveo

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter5: The Inheritance Of Complex Traits

Section: Chapter Questions

Problem 23QP: If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this...

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Piebald spotting is a condition found in humans in which there are patches of skin that lack pigmentation. The condition results from the inability of pigment-producing cells to migrate properly during development. Two adults with piebald spotting have one child who has this trait and a second child with normal skin pigmentation. a. Is the piebald spotting trait dominant or recessive? What information led you to this answer?
Galactosemia is a recessive human disease that istreatable by restricting lactose and glucose in the diet.Susan Smithers and her husband are both heterozygous for the galactosemia gene.a. Susan is pregnant with twins. If she hasfraternal (nonidentical) twins, what is theprobability both of the twins will be girls whohave galactosemia?b. If the twins are identical, what is the probabilitythat both will be girls and have galactosemia?For parts (c–g), assume that none of the children isa twin.c. If Susan and her husband have four children, whatis the probability that none of the four will havegalactosemia?d. If the couple has four children, what is the probability that at least one child will have galactosemia?e. If the couple has four children, what is the probability that the first two will have galactosemia andthe second two will not?f. If the couple has three children, what is the probability that two of the children will have galactosemia and one will not, regardless of order?g. If…
Albinism, a condition characterized by a partial or total lack ofskin pigment, is a recessive human trait. If a phenotypically unaffected couple produce an albino child, what is the probability thattheir next child will be albino?
A young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cysticfibrosis is a recessive disease, and neither member ofthe couple nor any of their four parents is affected.)a. What is the probability that the female of thiscouple is a carrier?b. What are the chances that their child will havecystic fibrosis?c. What is the probability that their child will be acarrier of the cystic fibrosis disease allele?
Suppose that a husband and wife are both heterozygous for a recessive allele for albinism. If they have dizygotic (two-egg) twins, what is the probability thatboth the twins will have the same phenotype forpigmentation?
Wooly hair is a rare dominant trait found in people of Scandinavian descent in which the hair resembles the wool of a sheep. Amale with wooly hair, who has a mother with straight hair, movesto an island that is inhabited by people who are not of Scandinavian descent. Assuming that no other Scandinavians immigrate tothe island, what is the probability that a great-grandchild of thismale will have wooly hair? (Hint: You may want to draw a pedigree to help you figure this out.) If this wooly-haired male haseight great-grandchildren, what is the probability that one out ofeight will have wooly hair?
Joan was born with six toes on each foot, a dominanttrait called polydactyly. Two of her five siblings and hermother, but not her father, also have extra digits. Whatis Joan’s genotype for the number-of-digits character?Explain your answer. Use D and d to symbolize the allelesfor this character.
Unattached earlobes (E) are dominant over attached earlobes (e) [Figure (a) and (b)]. If a woman with unattached earlobes and a man with attached earlobes have children, what percentage of their children has the possibility of having unattached earlobes if the mother is homozygous for the trait?
In humans, having freckles is dominant to not having freckles. What are the possible genotypes with someone with freckles?
In 1995, doctors reported a Chinese family in whichretinitis pigmentosa (progressive degeneration of theretina leading to blindness) affected only males. Allsix sons of affected males were affected, but all of thefive daughters of affected males (and all of thechildren of these daughters) were unaffected.a. What is the likelihood that this form of retinitispigmentosa is due to an autosomal mutationshowing complete dominance?b. What other possibilities could explain the inheritance of retinitis pigmentosa in this family? Whichof these possibilities do you think is most likely?
Retinitis pigmentosa, a form of blindness in man, maybe caused either by a dominant autosomal gene R, or a recessive autosomal gene a. An afflicted man whose parents are both normal marries a woman with genotype AaRr. a. What proportion of the children are expected to suffer from this affliction if R and A are inherited independently? b. If this couple want to have normal children only, what isthe probability of having normal children?
In humans, the gene for albinism (a) is recessive to the gene for normal skin pigmentation (A). If two heterozygous persons have children, what is the probability they will have a child who is an albino? What is the probability they will have a child that is a carrier of the recessive gene?