(please correct answer and correct and incorrect option explain) For autosomal dominant disease with incomplete penetrance, how can you distinguish carriers that are not expressing the disease from new mutation cases? A. detailed clinical evaluation of the patient B. A & B C. extended analysis of the family history D. sequencing the unaffected parents of affected individuals

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter28: Nucleic Acids
Section: Chapter Questions
Problem 28.37P
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(please correct answer and correct and incorrect option explain)

For autosomal dominant disease with incomplete penetrance, how can you distinguish carriers that are not expressing the disease from new mutation cases?

A. detailed clinical evaluation of the patient

B. A & B

C. extended analysis of the family history

D. sequencing the unaffected parents of affected individuals

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