Polysaccharide Storage Myopathy (PSM) is a dominant autosomal hereditary condition in horses that can cause muscle damage and inability to move. It is often referred to as “tying-up”. Equine hyperkalemic periodic paralysis (HYPP) is also a dominant autosomal hereditary condition in horses that has been traced back to a horse named Impressive who died in 1995 at the age of 26. Symptoms of HYPP include muscle twitching and unpredictable paralysis attacks that can lead to sudden death. Recall that with dominant disorders, only one dominant allele will result in the condition being manifested. a. A stallion with HYPP and PSSM whose mother had neither disorder is crossed with a mare who has neither HYPP or PSSM. Construct a punnett square and state the probability that this cross will result in a foal with neither HYPP or PSSM (think of this as a two-gene cross). b. What are the possible genotypes and phenotypes of all the foals? c. Probability of a foal without HYPP or PSSM?
9) Polysaccharide Storage Myopathy (PSM) is a dominant autosomal hereditary condition in horses that can cause muscle damage and inability to move. It is often referred to as “tying-up”. Equine hyperkalemic periodic paralysis (HYPP) is also a dominant autosomal hereditary condition in horses that has been traced back to a horse named Impressive who died in 1995 at the age of 26. Symptoms of HYPP include muscle twitching and unpredictable paralysis attacks that can lead to sudden death. Recall that with dominant disorders, only one dominant allele will result in the condition being manifested.
a. A stallion with HYPP and PSSM whose mother had neither disorder is crossed with a mare who has neither HYPP or PSSM. Construct a punnett square and state the probability that this cross will result in a foal with neither HYPP or PSSM (think of this as a two-gene cross).
b. What are the possible genotypes and
c. Probability of a foal without HYPP or PSSM?
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