A. What are the genotypes of the following: Jane: ______________________ James: ______________________ Jane’s mother: _________________ James’ mother: ________________ Jane’s father: __________________ James’ father: _________________ B. Should Jane and James marry and have children, what is the probability of having: a. a child with no X-linked disorders? ________________ b. a daughter with Fragile X-syndrome? _______________ c. a son with G6PDD?
Glucose-6-phosphate dehydrogenase deficiency/G6PDD (g) is an X-linked recessive condition
wherein the red blood cells of affected individuals undergo premature hemolysis. Fragile X syndrome
(F), on the other hand, is an X-linked dominant mutation characterized by a mild to moderate
intellectual disability. Amelogenesis imperfecta (A) is a congenital disorder affecting the formation of
the teeth enamel making affected individuals at higher risk for dental cavities and related problems.
Only male offspring inherit this condition.
Jane is heterozygous for both X-linked traits like her mother. Her father is normal for both X-
linked traits. James has a mother who suffers from G6PDD but not from fragile X-syndrome. His father
does not exhibit any X-linked disorder but has amelogenesis imperfecta.
A. What are the genotypes of the following:
Jane: ______________________ James: ______________________
Jane’s mother: _________________ James’ mother: ________________
Jane’s father: __________________ James’ father: _________________
B. Should Jane and James marry and have children, what is the probability of having:
a. a child with no X-linked disorders? ________________
b. a daughter with Fragile X-syndrome? _______________
c. a son with G6PDD?________________
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
