Posttranslational modifications of proteins do not include:peptide bond formationglycosylationacetylation of N-terminalpeptide bond cleavagedisulfide bond formationQUESTION 1614 15 16streptomycinpuromycin17 18 19 20Which one of the following antibiotics does NOT function by interfering with the translational/post-translation processtunicamycinpenicillinO tetracyclinOO

Proteins are one of the essential biomolecules for life. These are formed by translation from the…

Answered: Posttranslational modifications of…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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In posttranslational modification, phosphates are attached to which 3 amino acids? - tyrosine - serine - proline - lysine - threonine
Briefly describe each of the following possible posttranslational protein modifications. Give an example of each. Cross-linkage glycosylation and phosphorylation cleavage assembly into polymeric proteins (> 1 polypeptide)
Arrange the following components of translation in the approximate order in which they would appear or be used in prokaryotic protein synthesis, from first to last.30S initiation complex70S initation complexElongation Factor TuElongation Factor GInitiation Factor 3Release Factor 1fMet-TRNA fMet
What is the denaturant in Anfinsen’s classic experiment to demonstrate that reduced and denatured RNase A could refold into the native form? Urea. GroEL. 2-mercaptoethanol. Heat shock protein. Protein disulfide isomerase.
Which of the followinga.B-D-riboseb. thyminec. phosphatewhich is not a component of deoxyribonucleotide?
Consider the following coding 71 nucleotide DNA template sequence (It does not contain a translational start): 5’- GTTTCCCCTATGCTTCATCACGAGGGCACTGACATGTGTAAACGAAATTCCAACCTGAGCGGCGT GTTGAG-3’ By in vitro translating the mRNA, you determined that the translated peptide is 15 amino acids long. What is the expected peptide sequence in single letter abbreviations?
The images shown depict the initiation and elongation steps in protein translation. Arrange the images in the order in which these steps occur. A. B A C D B. B D A C C. C D A B D. A B C D
The following data describe the catalysis of cleavage of peptide bonds in small peptides by the enzyme UTSAse (the arrow indicates the peptide bond cleaved in each case). Substrate Km(mM) kcat(s-1) PAPA↓G 4.0 26 PAPA↓A 1.5 37 PAPA↓F 0.64 18 what features of amino acid sequence dictate the specificity of the proteolytic cleavage? Large hydrophilic R-groups Large hydrophobic R-groups Neutral R-groups Small hydrophilic R-groups Large hydrophobic R-groups Negatively charged R-groups Positively charged R-groups
Pro-CHEMBIO peptide is a large peptide sequence with three disulfide bonds (indicated by the lines between cysteine residues). CHEMBIO Protease cleaves amide bonds between two basic amino acid residues to give the final peptide that is active in the body. The products of this protease reaction are: 1. Two chains that make up active CHEMBIO peptide, which contain the N- and C-terminus sections of the original Pro-CHEMBIO molecule 2. A separate inactive peptide What if instead of CHEMBIO Protease, this peptide was cleaved by trypsin? Indicate the cleavage locations on the structure below. asap
When glycoproteins are synthesized in the cell, at what stage of the polymerization of the protein are the sugar groups added: Prior to translation, cotranslationally, or posttranslationally?
The following segment of DNA in a hypothetical model organism encodes a polypeptide containingSEVEN amino acids. Pretend this short polypeptide is a completely functional enzyme. DNA tripletsencoding the translation initiation (or start) codon and a stop codon are included in the sequence.3 •GGGTACGATCGGAAAGTTGGTTCICCGGTATAGCTG5'5•CCCATGCTAGCCTTTCAACAAAGAGGCCATATCGAC.3'a. Label which of the DNA strands is the template strand and which is coding strand. b. Below, show sequence and the polarity of the mRNA encoded by this 'gene'. Determine theamino acid sequence of the polypeptide (use three letter codes for the amino acids) andidentify the N- and C- terminal ends of the polypeptide. please help. I am confused. c. Which of the 7 side chains in this polypeptide can form hydrogen bonds with polar molecules(like water)? Place a circle around these.d. Some amino acids on a polypeptide can be modified post-translationally. Thesemodifications may have some effect on the function of the…
which of the following amino acids can undergo post-translational acetylation? A.n B.s C.k D.m

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