Provide the reagents, in order, that will allow for each of the distinct transformations of (3R,4S)-2,3-dimethylheptan-4-ol below. More than one step may be necessary NH2
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- Nitrating methyl benzoate. 1.Describe the mechanism of EAS clearly and in detail 2. What is the effect of subtituent of the outcome of EAS;include 3 classes of subtituentsWhy we need step 3 before step 4? a. Because the nitro group increases the electrophilicity at the ortho positions which is where the bromine is added. b. Because the amine group is a strong ortho, para director which is what controls the regiochemical outcome of this bromination. c. Step 4 is unessesary. The symmetry of compound 3 allows for the bromination to be regioselective and give compound 5. 5. There will be a mixture of products because there is no selectivity for a major product.Consider the reaction of 2-cyclopenten-1-one with neutral propan-2-amine, also called isopropylamine. 1. Draw the major product of the reaction
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