QUESTION 11 The location of five deletions have been mapped to a Drosophila chromosome, as shown in the following deletion map. Recessive mutations a, b, c, d and e are known to be located in the same region as the deletions but the order of the mutations on the chromosome is not known. Drosophila Chromosome Deletion 1 Deletion 2 Deletion 3 Deletion 4 Deletion 5 When flies homozygous for the recessive mutation are crossed with flies heterozygous for the deletions, the following results are obtained in which "m" represents recovery of flies with a mutant phenotype and "+" represents recovery of only flies with a wildtype phenotype. Use the data from the table below to determine the order of the genes (a-e) on the chromosome. Mutants Deletions a b C d e 1 + + + + m 2 + m + m 3 m m m m 4 + + m + + 5 m + m m + What is the gene order for these five genes? Please do not separate the letters representing the mutations with spaces or punctuation (e.g. LMNOP) When flies homozygous for the recessive mutation are crossed with flies heterozygous for the deletions, the following results are obtained in which "m" represents recovery of flies with a mutant phenotype and "+" represents recovery of only flies with a wildtype phenotype. Use the data from the table below to determine the order of the genes (a-e) on the chromosome. Deletions a b Mutants C 1 + + + m 2 + m + m + 3 m m m m 4 + + m + 5 m + m m + What is the gene order for these five genes? Please do not separate the letters representing the mutations with spaces or punctuation (e.g. LMNOP) In the table above, when there is an "m" in the box, the deletion chromosome (complements or fails to complement) the chromosome with the mutation.

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Chapter4: Pedigree Analysis In Human Genetics
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QUESTION 11
The location of five deletions have been mapped to a Drosophila chromosome, as shown in the following deletion map.
Recessive mutations a, b, c, d and e are known to be located in the same region as the deletions but the order of the
mutations on the chromosome is not known.
Drosophila Chromosome
Deletion 1
Deletion 2
Deletion 3
Deletion 4
Deletion 5
When flies homozygous for the recessive mutation are crossed with flies heterozygous for the deletions, the following
results are obtained in which "m" represents recovery of flies with a mutant phenotype and "+" represents recovery of
only flies with a wildtype phenotype. Use the data from the table below to determine the order of the genes (a-e) on the
chromosome.
Mutants
Deletions
a
b
C
d
e
1
+
+
+
+
m
2
+
m
+
m
3
m
m
m
m
4
+
+
m
+
+
5
m
+
m
m
+
What is the gene order for these five genes? Please do not separate the letters representing the mutations with
spaces or punctuation (e.g. LMNOP)
Transcribed Image Text:QUESTION 11 The location of five deletions have been mapped to a Drosophila chromosome, as shown in the following deletion map. Recessive mutations a, b, c, d and e are known to be located in the same region as the deletions but the order of the mutations on the chromosome is not known. Drosophila Chromosome Deletion 1 Deletion 2 Deletion 3 Deletion 4 Deletion 5 When flies homozygous for the recessive mutation are crossed with flies heterozygous for the deletions, the following results are obtained in which "m" represents recovery of flies with a mutant phenotype and "+" represents recovery of only flies with a wildtype phenotype. Use the data from the table below to determine the order of the genes (a-e) on the chromosome. Mutants Deletions a b C d e 1 + + + + m 2 + m + m 3 m m m m 4 + + m + + 5 m + m m + What is the gene order for these five genes? Please do not separate the letters representing the mutations with spaces or punctuation (e.g. LMNOP)
When flies homozygous for the recessive mutation are crossed with flies heterozygous for the deletions, the following
results are obtained in which "m" represents recovery of flies with a mutant phenotype and "+" represents recovery of
only flies with a wildtype phenotype. Use the data from the table below to determine the order of the genes (a-e) on the
chromosome.
Deletions
a
b
Mutants
C
1
+
+
+
m
2
+
m
+
m
+
3
m
m
m
m
4
+
+
m
+
5
m
+
m
m
+
What is the gene order for these five genes? Please do not separate the letters representing the mutations with
spaces or punctuation (e.g. LMNOP)
In the table above, when there is an "m" in the box, the deletion chromosome (complements or fails to complement)
the chromosome with the mutation.
Transcribed Image Text:When flies homozygous for the recessive mutation are crossed with flies heterozygous for the deletions, the following results are obtained in which "m" represents recovery of flies with a mutant phenotype and "+" represents recovery of only flies with a wildtype phenotype. Use the data from the table below to determine the order of the genes (a-e) on the chromosome. Deletions a b Mutants C 1 + + + m 2 + m + m + 3 m m m m 4 + + m + 5 m + m m + What is the gene order for these five genes? Please do not separate the letters representing the mutations with spaces or punctuation (e.g. LMNOP) In the table above, when there is an "m" in the box, the deletion chromosome (complements or fails to complement) the chromosome with the mutation.
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