Question 2: Consider the following pedigree, which traces the inheritance of a single-gene hereditary disease. Only individuals that are either affected or normal are shown. In other words, potential heterozygotes are NOT indicated. Assume that there is complete penetrance and no variable expressivity, and no new mutations. I II 5 IV Characterize each of the following modes of inheritance as impossible or possible. Justify your answers. Autosomal recessive b. Autosomal dominant C. X-linked recessive X-linked dominant Y-linked Sex-limited Sex influenced, dominant in males Sex influenced, dominant in females d. e £. 2 h. i. Mitochondrial inheritance
Question 2: Consider the following pedigree, which traces the inheritance of a single-gene hereditary disease. Only individuals that are either affected or normal are shown. In other words, potential heterozygotes are NOT indicated. Assume that there is complete penetrance and no variable expressivity, and no new mutations. I II 5 IV Characterize each of the following modes of inheritance as impossible or possible. Justify your answers. Autosomal recessive b. Autosomal dominant C. X-linked recessive X-linked dominant Y-linked Sex-limited Sex influenced, dominant in males Sex influenced, dominant in females d. e £. 2 h. i. Mitochondrial inheritance
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
Problem 2CS: Mike was referred for genetic counseling because he was concerned about his extensive family history...
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