Question 9: Solvent extraction A 150 mL aliquot of water contains 3.5 mg of compound X. (a) If the distribution ratio of X between water and methyl isobutyl ketone (MIBK) is 120, calculate the volume of MIBK is required to extract 95% of X in a single extraction. (b) Calculate the number of 10 mL extractions of MIBK needed to obtain 99% extraction efficiency.

Question 9: Solvent extraction A 150 mL aliquot of water contains 3.5 mg of compound X. (a) If the distribution ratio of X between water and methyl isobutyl ketone (MIBK) is 120, calculate the volume of MIBK is required to extract 95% of X in a single extraction. (b) Calculate the number of 10 mL extractions of MIBK needed to obtain 99% extraction efficiency.

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter31: Introduction To Analytical Separations

Section: Chapter Questions

Problem 31.12QAP

See similar textbooks

Similar questions

If you have 6.76 g of caffeine dissolved in 57.2 mL of water and the extraction coefficient between H2O and CH2Cl2 is 21.51. How many grams of caffeine will extract into the CH2Cl2 layer if you use 89.9 mL?
Prior to fat analysis, two samples: Sample 1 and Sample 2 with the initial weight for each sample=2.50g. After pre-dried, samples were grinded and reweighted; s1-2.15g and s2=2.11g. Samples were placed in dried glass wool in each thimble and placed extractor for 4-5 hours. Samples were then dried and cooled in desiccators before another weight recorded. The weight for s1=93.51g and for s2=93.78g #Weight of round bottom flask (with glass wool+ thimble) (g) = 92.00 #Weight of round bottom flask (g) =91.00 1) Calculate the percentage of dried fat in s1 2) Calculate the percentage of dried fat in s2. 3) Sample 3 have dried fats of 50%. Identify the correct sequence from the highest to the lowest % of dried fats in sample.
The alcohol content of hard liquor is normally given in terms of the “proof,” which is defined as twice the percentage by volume of ethanol (C2H5OH) present. Calculate the number of grams of alcohol present in 1.00 L of 75-proof gin. The density of ethanol is 0.798 g/mL. Round off to 4 sig. figures for all calculations made prior to final answer and the final answer should be in 3 sig. figures
4 If the concentration of Cu 0.5-80 ppm What are the ranges for kg of Cu present per metric ton?
1) How many milliliters of 70% ethanol and 20% ethanol must be mixed to prepare 500ml of 30% ethanol? 2) A gaseous blend of nitric oxide and nitrogen (NOmax) contains 0.09% v/v nitric oxide (NO) and 99.92% v/v nitrogen. Express the strength of nitric oxide in PPM (round to whole number) 3) The ratio strength of a 10mL vial of neostigmine methylsulfate injection USP is 1:1500.Calculate the amount of neostigmine methylsulfate in milligrams contained in the 10mL vial. (Round to the whole number).
Questions 4 and 5 pertain to the following scenario: The patient needs 500 g of the above ointment to use as part of phototherapy.4. Calculate the weight of betamethasone 0.05 % (w/w) ointment required, in grams.5. The above ratio is weight-based. Calculate the volume of mineral oil (sp gr = 0.85), in milliliters.
A sample of fried potatoes weighing 200 g was extracted using a volatile organicsolvent. The recovered cooking oil weighed 15 g. What methods from thisexperiment could be used to separate the cooking oil after the extraction? (evaporation, gravity filtration or vacuum filtration?) why so?
Prepare 100 μL of 10.0 mM hydrolyzed sucrose in 10.0 mM acetate pH 4.8 as a standard, in a 1.5 mL microcentrifuge tube, also incorporating 5.00 μL of 5.0 mM tris pH 7.4 within the 100 μL volume. Using a stock solution of 20.0 mM sucrose substrate in 10.0 mM acetate, calculate the volumes of hydrolyzed sucrose, acetate, and dH2O.
Indicate the appropriate protocol below to prepare the required solution. a) Solution 5 Preparation: Prepare: 10 mL of 23% mannitol From: solid mannitol Procedure: b) Solution 2 Preparation: Prepare: 0.5 liters of 0.01 mg/mL ascorbic acid From: solid ascorbic acid , MW = 176.1 g/mol Procedure: C) Solution 3 Preparation: Prepare: 1 liter of 150 mM Tris From: 1 Molar Tris stock solution Procedure:
Measure the mass of 0.400g of Co(NO3)2 + 6H2O and dissolve it in 15mL of distilled or deionized water using a clean beaker Then while using a graduated cylinder, measure out 10.0mL of a prepared 0.10-M Na3PO4 soultion. Determine which compound Na3PO4 or Co(NO3)2 *6H2O will be the limliting reagent. Then detrimine the theiretical yeild
According to the USP, the percentage purity of ascorbic acid in tablets must be 90.0% to 110.0%. The amount of pure ascorbic acid determined after the assay procedure was 0.3226 g. If the weight of the sample used was 0.4529 g and the average weight of five 500-mg tablets was 0.6185, the sample conforms to the USP specifications. True False
A cellulose sponge, 7.0cm x 12cm x 2.5cm, weights 12.0 grams. Calculate the specific gravity of the sponge.