Radiopaque imaging agents are substances administered either orally or intrave- nously that absorb X-rays more strongly than body material. One of the best known of these is barium sulfate, the key ingredient in the so-called barium cocktail for imaging of the gastrointestinal tract. Among other X-ray contrast media are the so- called triiodoaromatics. You can get some idea of the imaging for which they are used from the following selection of trade names: Angiografin, Gastrografin, Cardiografin, Cholegrafin, Renografin, and Urografin. Following is a synthesis for diatrizoic acid from benzoic acid. СООН COOH COOH NO2 (3) NO2 O,N COOH COOH СООН I ICI 4 NH2 H,N NH2 H,N 'N' `N' I I H H Diatrizoic acid

Principles of Instrumental Analysis
7th Edition
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Chapter16: An Introduction To Infrared Spectrometry
Section: Chapter Questions
Problem 16.16QAP
icon
Related questions
icon
Concept explainers
Question

Iodine monochloride, ICl, a black crystalline solid with an mp of 27.2°C and a bp of 97°C, is prepared by mixing equimolar amounts of I2 and Cl2. Propose a mechanism for the iodination of 3-aminobenzoic acid by this reagent.

Radiopaque imaging agents are substances administered either orally or intrave-
nously that absorb X-rays more strongly than body material. One of the best known
of these is barium sulfate, the key ingredient in the so-called barium cocktail for
imaging of the gastrointestinal tract. Among other X-ray contrast media are the so-
called triiodoaromatics. You can get some idea of the imaging for which they are used
from the following selection of trade names: Angiografin, Gastrografin, Cardiografin,
Cholegrafin, Renografin, and Urografin. Following is a synthesis for diatrizoic acid
from benzoic acid.
СООН
COOH
COOH
NO2
(3)
NO2
O,N
COOH
COOH
СООН
I
ICI
4
NH2
H,N
NH2
H,N
'N'
`N'
I
I
H
H
Diatrizoic acid
Transcribed Image Text:Radiopaque imaging agents are substances administered either orally or intrave- nously that absorb X-rays more strongly than body material. One of the best known of these is barium sulfate, the key ingredient in the so-called barium cocktail for imaging of the gastrointestinal tract. Among other X-ray contrast media are the so- called triiodoaromatics. You can get some idea of the imaging for which they are used from the following selection of trade names: Angiografin, Gastrografin, Cardiografin, Cholegrafin, Renografin, and Urografin. Following is a synthesis for diatrizoic acid from benzoic acid. СООН COOH COOH NO2 (3) NO2 O,N COOH COOH СООН I ICI 4 NH2 H,N NH2 H,N 'N' `N' I I H H Diatrizoic acid
Expert Solution
steps

Step by step

Solved in 2 steps with 1 images

Blurred answer
Knowledge Booster
Aromatic Compounds
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning