In recessively inherited disorders, a carrier is an individualwho has one copy of the recessive gene but does not exhibitthe disorder.Cystic fibrosis is a recessively inherited disorder that runs inAnn's family. Ann has created the pedigree based on what sheknows about her family's history.AWhich individuals can Ann assume are carriers of thecystic fibrosis gene without performing anygenetic testing? Select all that apply.O Ann's sisterAnn's auntAnn's grandfatherAnn's mother

Name: In recessively inherited disorders, a carrier is an individualwho has
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Description: In recessively inherited disorders, a carrier is an individualwho has one copy of the recessive gene but does not exhibitthe disorder.Cystic fibrosis is a recessively inherited disorder that runs inAnn's family. Ann has created the pedigree based on

Cystic Fibrosis: CF is a form of autosomal recessive genetic disorder caused by genetic modification…

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Biology

recessively inherited disorders, a can who has one copy of the recessive gen the disorder. Cystic fibrosis is a recessively inherite Ann's family. Ann has created the pedi knows about her family's history.

recessively inherited disorders, a can who has one copy of the recessive gen the disorder. Cystic fibrosis is a recessively inherite Ann's family. Ann has created the pedi knows about her family's history.

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter19: Introduction To Genetics

Section: Chapter Questions

Problem 7CT

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a human disease known as cystic fibrosis is inherited as a recessive trait.Two unaffected individuals have a first child with the disease. What isthe probability that their next two children will not have the disease?
A young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cysticfibrosis is a recessive disease, and neither member ofthe couple nor any of their four parents is affected.)a. What is the probability that the female of thiscouple is a carrier?b. What are the chances that their child will havecystic fibrosis?c. What is the probability that their child will be acarrier of the cystic fibrosis disease allele?
Attached are three pedigrees. For each trait, considerwhether it is or is not consistent with X-linked recessiveinheritance. In a sentence or two, indicate why or why not.
Huntington disease is a rare fatal, degenerative neurological disease in which individuals start to showsymptoms in their 40s. It is caused by a dominant allele. Joe, a man in his 20s, just learned that his fatherhas Huntington disease.a. What is the probability that Joe will also developthe disease?b. Joe and his new wife have been eager to start afamily. What is the probability that their first childwill eventually develop the disease?
Karen and Steve each have a sibling with sickle-cell disease.Neither Karen nor Steve nor any of their parents have thedisease, and none of them have been tested to see if they carrythe sickle-cell allele. Based on this incomplete information,calculate the probability that if this couple has a child, thechild will have sickle-cell disease.
Piebald spotting is a condition found in humans inwhich there are patches of skin that lack pigmentation. The condition results from the inability ofpigment-producing cells to migrate properly duringdevelopment. Two adults with piebald spotting haveone child who has this trait and a second child withnormal skin pigmentation.a. Is the piebald spotting trait dominant or recessive?What information led you to this answer?b. What are the genotypes of the parents?
Wooly hair is a rare dominant trait found in people of Scandinavian descent in which the hair resembles the wool of a sheep. Amale with wooly hair, who has a mother with straight hair, movesto an island that is inhabited by people who are not of Scandinavian descent. Assuming that no other Scandinavians immigrate tothe island, what is the probability that a great-grandchild of thismale will have wooly hair? (Hint: You may want to draw a pedigree to help you figure this out.) If this wooly-haired male haseight great-grandchildren, what is the probability that one out ofeight will have wooly hair?
a. The ability to taste the chemical phenylthiocarbamideis an autosomal dominant phenotype, and the inabilityto taste it is recessive. If a taster woman with a nontasterfather marries a taster man who in a previous marriagehad a nontaster daughter, what is the probability thattheir first child will be(1) A nontaster girl(2) A taster girl(3) A taster boyb. What is the probability that their first two childrenwill be tasters of either sex?
A woman who is heterozygous, Bb, has brown eyes; B (brown) isthe dominant allele, and b (blue) is recessive. One of her eyes,however, has a patch of blue color. Give three different explanationsfor how this might have occurred?
Joan was born with six toes on each foot, a dominanttrait called polydactyly. Two of her five siblings and hermother, but not her father, also have extra digits. Whatis Joan’s genotype for the number-of-digits character?Explain your answer. Use D and d to symbolize the allelesfor this character.
Zoe has cystic fibrosis. Which of the following is themost likely explanation?a. Zoe probably inherited one faulty allele from herfather, who is a carrier, and one normal allelefrom her mother.b. Zoe probably inherited one faulty allele from hermother, who must also have cystic fibrosis, andone normal allele from her father.c. Zoe must have inherited faulty alleles from bothparents, both of whom must also have cysticfibrosis.d. Zoe must have inherited faulty alleles from bothparents, both of whom are carriers.
. Tay-Sachs disease is a rare human disease in which toxic substances accumulate in nerve cells. The recessiveallele responsible for the disease is inherited in a simpleMendelian manner. For unknown reasons, the allele ismore common in populations of Ashkenazi Jews ofeastern Europe. A woman is planning to marry her firstcousin, but the couple discovers that their sharedgrandfather’s sister died in infancy of Tay-Sachsdisease.a. Draw the relevant parts of the pedigree, and showall the genotypes as completely as possible.b. What is the probability that the cousins’ first childwill have Tay-Sachs disease, assuming that all peoplewho marry into the family are homozygous normal?