Research how the CD28/B7 and CTLA-4/B7 interactions are being targeted in the development of new therapeutic drugs. - Briefly summarize the functions of CD28 and CTLA-4 and summarize in concept why they represent attractive therapeutic targets. - What kinds of diseases could potentially be treated by such drugs? Explain why. Identify at least one new drug that is either already in use or under development which targets either of these molecules; and include the following information: the company or research institute, the stage of development of the drug, the disease that is being treated. - What alternative therapies if any exist for this disease? - Does this drug offer a better alternative to current treatments? Why or why not? - What do you think are the pros/cons with the use of this drug? - At the end of your report include an open-ended and provocative question that will inspire your classmates to respond to your report.

Research how the CD28/B7 and CTLA-4/B7 interactions are being targeted in the development of new therapeutic drugs. - Briefly summarize the functions of CD28 and CTLA-4 and summarize in concept why they represent attractive therapeutic targets. - What kinds of diseases could potentially be treated by such drugs? Explain why. Identify at least one new drug that is either already in use or under development which targets either of these molecules; and include the following information: the company or research institute, the stage of development of the drug, the disease that is being treated. - What alternative therapies if any exist for this disease? - Does this drug offer a better alternative to current treatments? Why or why not? - What do you think are the pros/cons with the use of this drug? - At the end of your report include an open-ended and provocative question that will inspire your classmates to respond to your report.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter41: Neural Signaling

Section: Chapter Questions

Problem 11TYU

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