serotonin [uM] 0.025 0.08 0.25 0.7 2 6 transport rate A [dpm/min] 300.0 920.0 2500.0 5400.0 8800.0 9100.0 transport rate B [dpm/min] 10 30.0 100.0 350.0 1100.0 3000.0 11. Draw a graph (by using Excel or similar), plotting the serotonin concentration against the transport rate under both conditions.

Biomedical Instrumentation Systems
1st Edition
ISBN:9781133478294
Author:Chatterjee
Publisher:Chatterjee
Chapter13: Artifacts And Noise In Medical Instrumentation
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serotonin [µM]
0.025
transport rate A [dpm/min]
300.0
transport rate B [dpm/min]
10
0.08
920.0
30.0
0.25
2500.0
100.0
0.7
5400.0
350.0
2
8800.0
1100.0
9100.0
3000.0
11. Draw a graph (by using Excel or similar), plotting the serotonin concentration against the
transport rate under both conditions.
12. What transport rates for each condition would you expect if the experiment was repeated
using 12µM ['H] serotonin? Add your estimate into the table above.
13. Examine the plot obtained for condition A; what can you conclude with regards to
whether or not the transport of serotonin into these cells requires a protein? Explain your
conclusion.
14. Compare the plots of the transport rates for both conditions. What is most likely
mechanism of transport for serotonin into these cells? Explain your interpretation.
Transcribed Image Text:serotonin [µM] 0.025 transport rate A [dpm/min] 300.0 transport rate B [dpm/min] 10 0.08 920.0 30.0 0.25 2500.0 100.0 0.7 5400.0 350.0 2 8800.0 1100.0 9100.0 3000.0 11. Draw a graph (by using Excel or similar), plotting the serotonin concentration against the transport rate under both conditions. 12. What transport rates for each condition would you expect if the experiment was repeated using 12µM ['H] serotonin? Add your estimate into the table above. 13. Examine the plot obtained for condition A; what can you conclude with regards to whether or not the transport of serotonin into these cells requires a protein? Explain your conclusion. 14. Compare the plots of the transport rates for both conditions. What is most likely mechanism of transport for serotonin into these cells? Explain your interpretation.
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