Sickle cell disease is caused by a recessive allele. Individuals with two recessive alleles usually die of sickle cell disease before reaching reproductive age. However, individuals with only one recessive allele show few of the symptoms of the disease. The frequency of the sickle cell gene seems to be highest in populations of central Africa, a region where malaria is common. a) Do heterozygous individuals have a survival advantage over homozygous individuals in this region? Why?

Biology: The Dynamic Science (MindTap Course List)
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ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
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Chapter21: Microevolution: Genetic Changes Within Populations
Section: Chapter Questions
Problem 12TYK: Discuss Concepts Many human diseases are caused by recessive alleles that are not expressed in...
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2. Sickle cell disease is caused by a recessive allele. Individuals with two recessive alleles usually
die of sickle cell disease before reaching reproductive age. However, individuals with only one
recessive allele show few of the symptoms of the disease. The frequency of the sickle cell
gene seems to be highest in populations of central Africa, a region where malaria is common.
a) Do heterozygous individuals have a survival advantage over homozygous individuals in this
region? Why?
b) Do you think the frequency of the sickle cell allele is higher or lower in Canada as
compared to Africa? Explain your answer fully.
Transcribed Image Text:2. Sickle cell disease is caused by a recessive allele. Individuals with two recessive alleles usually die of sickle cell disease before reaching reproductive age. However, individuals with only one recessive allele show few of the symptoms of the disease. The frequency of the sickle cell gene seems to be highest in populations of central Africa, a region where malaria is common. a) Do heterozygous individuals have a survival advantage over homozygous individuals in this region? Why? b) Do you think the frequency of the sickle cell allele is higher or lower in Canada as compared to Africa? Explain your answer fully.
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