, within specific regional populations over two thousand years ago, sickle-cell anemia killed those individuals born with it before they could reproduce to pass it on to offspring, how did it persist in these populations?

Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter20: Chromosomes And Human Genetics
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Problem 6CT: About 4 percent of people of Northern European descent have a cystic fibrosis allele, but only about...
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If, within specific regional populations over two thousand years ago, sickle-cell anemia killed those individuals born with it before they could reproduce to pass it on to offspring, how did it persist in these populations? 
Group of answer choices
A-Because of late-onset of the disease.
B-Because it is cause by a virus and it spreads faster than people died.
C-Because of the basic principles of mendelian inheritance that result in some heterozygote "carrier" combinations.
D-Because malaria made it possible to survive sickle cell anemia since the parasite would carry oxygen on the blood cells with the mutated hemoglobin.
E-It does not persist. Natural selection removes the allele because people die from both malaria and sickle-cell anemia.
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