Solution Absorbance mg/ml aspirin Standard solution - 1.6 mg/mL A 0.638 0.08 mg/mL B 0.504 0.064 mg/mL C 0.376 0.048 mg/mL D 0.259 0.032 mg/mL E 0.126 0.016 mg/mL A = -log T where T = %T ÷ 100 Construct a callibration curve using the above data. Absorbance should be on the vertical axis and "mg/mL of acetylsalicylic acid" on the horizontal axis. The line should go through the origin. Using the data provided, the graph you have generated, and the procedure that was used to generate the solutions which were examined by spectroscopy, calculate the amount of acetylsalicylic acid per tablet. Commercial tablet 1 labelled as 100 mg enteric coated Absorbance = 0.16 Commercial tablet 2 labelled as 300 mg Absorbance = 0.45 Student prepared tablet from practical 5 Absorbance = 0.19 Using the data provided, the graph you have generated, and the procedure that was used to generate the solutions which were examined by spectroscopy, calculate the amount of acetylsalicylic acid per tablet. You must show and explain your calculations in the answer provided. Commercial tablet 1 labelled as 100 mg enteric coated Absorbance = 0.16 Commercial tablet 2 labelled as 300 mg Absorbance = 0.45 Student prepared tablet from practical 5 Absorbance = 0.19 The aspirin tablet was not hydrolysed using sodium hydroxide in this experiment, any salicylic acid detected would be present in the tablet. Using the absorbance value determined for the solution in part C, calculate the amount of salicylic acid (not aspirin) present in the tablet, and therefore the purity of the tablet. 300 mg tablet had an absorption of 0.06
|
Solution |
Absorbance |
mg/ml aspirin |
|
Standard solution |
- |
1.6 mg/mL |
|
A |
0.638 |
0.08 mg/mL |
|
B |
0.504 |
0.064 mg/mL |
|
C |
0.376 |
0.048 mg/mL |
|
D |
0.259 |
0.032 mg/mL |
|
E |
0.126 |
0.016 mg/mL |
A = -log T where T = %T ÷ 100
Construct a callibration curve using the above data. Absorbance should be on the vertical axis and "mg/mL of acetylsalicylic acid" on the horizontal axis. The line should go through the origin.
Using the data provided, the graph you have generated, and the procedure that was used to generate the solutions which were examined by spectroscopy, calculate the amount of acetylsalicylic acid per tablet.
Commercial tablet 1 labelled as 100 mg enteric coated Absorbance = 0.16Commercial tablet 2 labelled as 300 mg Absorbance = 0.45
Student prepared tablet from practical 5 Absorbance = 0.19
Using the data provided, the graph you have generated, and the procedure that was used to generate the solutions which were examined by spectroscopy, calculate the amount of acetylsalicylic acid per tablet.
You must show and explain your calculations in the answer provided.
Commercial tablet 1 labelled as 100 mg enteric coated Absorbance = 0.16
Commercial tablet 2 labelled as 300 mg Absorbance = 0.45
Student prepared tablet from practical 5 Absorbance = 0.19
The aspirin tablet was not hydrolysed using sodium hydroxide in this experiment, any salicylic acid detected would be present in the tablet. Using the absorbance value determined for the solution in part C, calculate the amount of salicylic acid (not aspirin) present in the tablet, and therefore the purity of the tablet.
300 mg tablet had an absorption of 0.06
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