Statin drugs are used to treat hypercholesterolemia because they a. prevent cholesterol from inserting in plasma membranes b. prevent cholesterol ester formation c. inhibit HMG-CoA reductase d. stimulate HMG-CoA synthase
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Statin drugs are used to treat hypercholesterolemia because they
a. prevent cholesterol from inserting in plasma membranes
b. prevent cholesterol ester formation
c. inhibit HMG-CoA reductase
d. stimulate HMG-CoA synthase
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- Acetyl CoA is generated from ________. A. oxaloacetate B. pyruvic acid C. citric acid D. waterBile salts are responsible for the... A. transport of triacylglycerols to adipocytes. B. transport of fatty acids from adipocytes to myocytes. C. exposure of triacylglycerols to intestinal lipases. D. prevention of triacylglycerol to diacylglycerol degradation.Pyruvate dehydrogenase deficiency, a severe condition with a poor prognosis, results in neurological dysfunction and unremitting lactic acidosis. One treatment is placing the patients on a low carbohydrate/high fat diet. ( a) Explain why the deficiency would be characterized by neurological dysfunction. ( b) Why does lactic acidosis result? ( c) Explain the rationale for the low carbohydrate/high fat diet.
- When one acetyl CoA is processed through the citric acid cycle, how many times does each of the following events occur? a. A FAD molecule is a reactant. b. A CoA-SH molecule is produced. c. A dehydrogenase enzyme is needed for the reaction to occur. d. A C5 molecule is produced.Which of the following stimulates the conversion of pyruvate to acetyl-CoA? a) Activation of pyruvate dehydrogenase kinase b) A decrease in the ratio of NAD+/NADH c) Bothaandb d) Neither a nor bIf you fed a mouse a diet made up of exclusively Leucine, the mouse would eventually: A、Undergo extensive gluconeogenesis B、Enter ketosis C、Have a buildup of α-Ketoglutarate D、gain weight E、have a buildup of succinyl-CoA
- Which of the following enzymes possesses a catalytic mechanism extremely similar to that of the Pyruvate Dehydrogenase Complex? A. the isocitrate dehydrogenase B. the succinate dehydrogenase C. the alpha-ketoglutarate dehydrogenase D. the malate dehydrogenaseCO2 is released when A. creating a thioester bond between acetyl-CoA and acyl-carrier protein B. two carbons from malonyl-ACP is transferred to acetyl-ACP C. exchanging substituents on adjacent carbon atoms. D. converting a hydroxyl group to an enoylA patient complains of painful muscle cramps when performing strenuous physical exercise. A muscle biopsy indicates a higher than normal concentration of muscle glycogen. a. Which enzyme of glycogen metabolism is affected? b. Discuss how the defect of this enzyme affects glycogen metabolism.
- If an individual has impaired respiratory function, as occurs with emphysema, you would expect all of the following except a. production of additional lactate. b. an impaired ability to make ATP. c. low energy levels and complaints of being tired. d. increased aerobic cellular respiration.Acetyl-CoA can be synthesized a. By pyruvate dehydrogenase or fatty acid ?-oxidation b. All the answers are true c. From pyruvate or fatty acids d. In the matrix of the mitochondriaWhich of these statements about lactate dehydrogenase is true? a.It is a protein. b.It oxidizes lactic acid. c.It reduces another molecule (pyruvic acid). d.All of these are true.