A patient complains of painful muscle cramps when performing strenuous physical exercise. A muscle biopsy indicates a higher than normal concentration of muscle glycogen. a. Which enzyme of glycogen metabolism is affected? b. Discuss how the defect of this enzyme affects glycogen metabolism.
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A patient complains of painful muscle cramps when performing strenuous physical exercise. A muscle biopsy indicates a higher than normal concentration of muscle glycogen.
a. Which enzyme of glycogen
b. Discuss how the defect of this enzyme affects glycogen metabolism.
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- what effect would an increase in glucose typically have on the activity of glycogen synthaseWhich one of the following is NOT a metabolic effect of glucagon secretion? Select one: a. Increase in gluconeogenesis. b. Increased glycogenolysis. c. Increase in the activity of adenylate cyclase. d. Increased amino acid uptake by the muscles.Briefly explain the importance of vitamin C in the function of Prolyl hydroxylase enzyme? and what disease resulted from its deficiency?
- Which of these statements about lactate dehydrogenase is true? a.It is a protein. b.It oxidizes lactic acid. c.It reduces another molecule (pyruvic acid). d.All of these are true.The enzyme involved in the formation of fructose-6-phosphate is a/an A. isomerase B. aldolase C. transketolase D. transaldolasePyruvate dehydrogenase deficiency, a severe condition with a poor prognosis, results in neurological dysfunction and unremitting lactic acidosis. One treatment is placing the patients on a low carbohydrate/high fat diet. ( a) Explain why the deficiency would be characterized by neurological dysfunction. ( b) Why does lactic acidosis result? ( c) Explain the rationale for the low carbohydrate/high fat diet.
- What is the effect of insulin on the committed step of glycolysis in the liver? Describe the mechanism by which insulin can affect the activity of this enzyme in the liver?A)Explain the IMPORTANCE OF GLUCOSIS-6-PHOSPHATE FOR METABOLISM B)SHOW THE REACTIONS WHERE GLUCOSE-6-PHOSPHATE IS OBTAINED AND USED BY WRITING AND EXPLAINING THE REGULATIONS.Which of these fatty acids is most oxidized? a b c d
- Explain the functions of insulin. Why do you think a hormone such asinsulin is required to carry out these functions?Islet cells in the pancreas are actively synthesizing and secreting insulin into the bloodstream. A scientist purifies different membranous fractions of these islet cells. In which fraction would she find insulin or its intermediates?Describe the effects of a diet that includes large amounts of fructose.