Step 6 of the citric acid cycle is shown. Which statement best describes the role ofFAD in this reaction?CH₂lalCH₂FADFADH₂ CO₂CO₂succinateCHCHfumarateOA) FAD causes the oxidation of succinate to form fumarate.B) FAD causes succinate to undergo hydration to form fumarate.C) FAD causes the isomerication of succinate to form fumarate.D) FAD causes the reduction of succinate to form fumarate.

Citric acid cycle is a metabolic pathway that regenerates oxaloacetate from citrate. Acetyl CoA from…

Answered: Step 6 of the citric acid cycle is…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Characterize, in terms of number of carbon atomspresent, each of the following citric acid cycle changesas (1) a C4 to C4 change, (2) a C4 to C6 change, (3) a C5to C4 change, or (4) a C6 to C5 change.a. Oxaloacetate to citrateb. a-Ketoglutarate to succinyl CoAc. Fumarate to malated. Succinyl CoA to succinate
Which of the following is the second step of Citric Acid Cycle? Select one: a. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH b. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH c. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH d. Malate is oxidized to become oxaloacetate forming NADH e. Fumarate is combined with water to become Malate f. Citrate is rearranged to become Isocitrate g. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide h. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) i. Succinate is oxidized to become fumarate forming FADH2
Which of the following statements is/are TRUE for the Krebs' cycle? Reaction 1: condensation of acetyl-CoA and oxaloacetate; produces H20. Reaction 3: oxidation of isocitrate to a-ketoglutarate; produces NADH and CO2. Reaction 6: oxidation of succinate to fumarate; produces FADH2 and CO2 Reaction 5: hydrolysis of succinyl-CoA to succinate; produces ATP.
Which of the following is the sixth step of Citric Acid Cycle? Select one: a. Succinate is oxidized to become fumarate forming FADH2 b. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH c. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH d. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) e. Malate is oxidized to become oxaloacetate forming NADH f. Fumarate is combined with water to become Malate g. Citrate is rearranged to become Isocitrate h. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide i. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH
identify the reactions of the citric acid cycle that provide reducing power for the electron-transport chain a. conversion of succinyl-CoA to succinate b. conversion of fumarate to malate c. conversion of succinate to fumarate d. conversion of malate to oxaloacetate
What citric acid cycle intermediate would be regenerated?
Do any of the respiratory complexes play a role in the citric acid cycle? If so, what is that role?
How many times must the TCA cycle be performed to oxidize one molecule of glucose completely to six molecules of CO2? Why?
What step in the citric acid cycle in inhibited by fluorocitrate?
How is succinate dehydrogenase unique compared with the other enzymes in the citric acid cycle?
Why is it that the carboxylate "ions" actually partake in the citric acid cycle ratherthan the carboxylic acid? Explain using an example
in steps 3 and 5 of the citric acid cycle, the compounds are shortended by one carbon each time. whst is the form of this one-carbon compound? what happens to it in the body?

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