Studies have demonstrated a marked interindividual variation in the pharmacokinetics and pharmacodynamics of oxycodone, which raises questions about its effect on the reduction of pain over time in the population. Extended-release tablets are available in 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg and 80 mg strengths. A new patient is suffering from chronic lower back pain and is on 30 mg twice a day. The patient says the pain remains high. What are possible explanations?
Musculoskeletal System
The musculoskeletal system, also called the locomotor system, is an organ system that gives humans and animals the ability to move using their muscular and skeletal systems. It provides stability, form, support, and movement to the body. The skeleton is composed of bones (skeleton), muscles, cartilage, tendons, ligaments, joints, and other connective tissue that supports and binds tissues and organs together. The musculoskeletal system is subdivided into two broad systems, such as the muscular system and the skeletal system.
Skeletal structure
The skeletal system is the core framework of the human body. The skeletal structure comprises bones and connective tissue, including cartilage, ligaments, and tendons. The skeletal structure of our body acts as a support structure. It maintains the body's shape and is responsible for its movement, blood cell formation, protection of organs, and mineral storage. The skeletal system is referred to as the musculoskeletal system.
Studies have demonstrated a marked interindividual variation in the pharmacokinetics and pharmacodynamics of oxycodone, which raises questions about its effect on the reduction of pain over time in the population. Extended-release tablets are available in 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg and 80 mg strengths. A new patient is suffering from chronic lower back pain and is on 30 mg twice a day. The patient says the pain remains high. What are possible explanations?
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